Evidence map›Paper›PMID 41759460›Full record

ArticleClinical biomechanics (Bristol, Avon)2026

Muscle architecture predicts lower extremity power generation during a power leg press test in individuals with cerebral palsy.

Mattie E Pontiff, Evrim Oral, Noelle G Moreau

Abstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mattie E PontiffSchool of Allied Health Professions, Department of Physical Therapy, Louisiana State University Health Sciences Center - New Orleans, New Orleans, LA 70112, USA.
Evrim OralBiostatistics & Data Science School of Public Health LSUHSC-New Orleans 2020, Gravier Street, 3rd Floor, New Orleans, LA 70112, USA.
Noelle G MoreauSchool of Allied Health Professions, Department of Physical Therapy, Louisiana State University Health Sciences Center - New Orleans, New Orleans, LA 70112, USA. Electronic address: nmorea@lsuhsc.edu.

Funding

Power Training Combined with Interval Treadmill Training to Improve Walking Activity in Cerebral PalsyR01HD091089 · NICHD · LSU HEALTH SCIENCES CENTER · PI MOREAU, NOELLE G · 2018 to 2022
$2.5M
NICHD NIH HHS R01 HD091089
6 · The paper itself

Abstract

backgroundThe purpose of this cross-sectional study was to examine relationships between power and muscle architecture in individuals with cerebral palsy (CP).

methodsParticipants (n = 26; 19.3 ± 7.8 years; range 10-37 years; Gross Motor Function Classification System level I-III) performed 5 power leg presses with the concentric performed at a high velocity. Peak Power was calculated as the highest power value across the 5 presses. Architectural outcomes were muscle thickness, cross-sectional area, and fascicle length of the vastus lateralis, medial gastrocnemius, and rectus femoris. Simple linear and multiple regression were used to examine associations between architecture and Peak Power.

findingsPeak Power was positively associated with all architectural variables (p < 0.05) except for rectus femoris fascicle length (p = 0.058). Rectus femoris thickness alone explained the greatest variance in Peak Power (50.8%). Rectus femoris and medial gastrocnemius cross-sectional area combined with fascicle length of each muscle explained between 68.5%-69.2% of the variance in Peak Power (p < 0.001). Rectus femoris cross-sectional area, age, and Gross Motor Function level together explained 71.6% of the variance in Peak Power (p < 0.001).

interpretationMuscle architecture is a significant predictor of lower extremity muscle power in individuals with CP. Muscle size was a stronger predictor of power than fascicle length; however, combining these variables substantially increased model strength, explaining 69% of the variance in power. The addition of age and Gross Motor Function level provided additional explanatory power. These findings highlight the key role of muscle architecture in muscle performance in individuals with CP.

Indexed as

Cerebral PalsyLegLower ExtremityMuscle, SkeletalMuscle StrengthAdolescentAdultChildCross-Sectional StudiesFemaleHumansMaleMuscle ContractionYoung AdultCerebral palsyCross-sectional areaFascicle lengthMuscle architecturePowerStrength

Identifiers

PMID41759460
PMCPMC13483056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.