Evidence map›Paper›PMID 41758455›Full record

ArticleInfection2026

A rare complication in humans of a rare disease in Germany: a case of bilateral tubo-ovarian abscesses caused by Brucella melitensis.

Sabine Zange, Mike H Pillukat, Kristina Wohlfart, August Stich, Hans-Peter Maidhof, Michael Seidel, Daniel Lang, Enrico Mantel

Abstract readCase Reports
In one paragraph

Article in Infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sabine ZangeBundeswehr Institute of Microbiology, Munich, Germany. sabinezange@bundeswehr.org.ORCID http://orcid.org/0000-0001-8721-9248
Mike H PillukatBundeswehr Institute of Microbiology, Munich, Germany.ORCID http://orcid.org/0000-0002-7599-2038
Kristina WohlfartDepartment of General Surgery, University Hospital Regensburg, Regensburg, Germany.
August StichDepartment of Infectious Diseases and Tropical Medicine, University Hospital Würzburg, Würzburg, Germany.ORCID http://orcid.org/0009-0008-2520-9755
Hans-Peter MaidhofDepartment of Microbiology, Institute of Laboratory Medicine, Klinikum Fürth, Fürth, Germany.ORCID http://orcid.org/0009-0007-2353-934X
Michael SeidelBundeswehr Institute of Microbiology, Munich, Germany.ORCID http://orcid.org/0000-0003-2074-6443
Daniel LangBundeswehr Institute of Microbiology, Munich, Germany.ORCID http://orcid.org/0000-0002-2166-0716
Enrico MantelBundeswehr Institute of Microbiology, Munich, Germany.ORCID http://orcid.org/0000-0003-0819-0681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrucellosis, caused by the gram-negative bacterium Brucella spp. (mainly by B. melitensis, B. abortus or B. suis) is one of the most widespread neglected zoonotic diseases. The global number of human cases is underestimated due to the lack of comprehensive surveillance systems in endemic regions. In Germany, brucellosis is a notifiable disease and case counts are stable at low levels with around 30-40 cases per year. Almost all cases are imported from endemic regions like the Mediterranean basin and the Middle East. Different Brucella spp. are pathogenic for a wide variety of animals and typical sites of infection are the reproductive organs (both in female and male animals). In humans, involvement of the female genito-urinary system is rare and only a few cases have been reported. CASE PRESENTATION: Here, we present a clinical case of bilateral tubo-ovarian abscesses with spread to the appendix in a 29-year-old woman of Bosnian origin, that was caused by Brucella melitensis

conclusionsOur report discusses the lessons learned from this rare complication of brucellosis in a non-endemic region, scrutinizes the involvement of a dermoid cyst as hideout for chronic infection and summarizes current data on brucellosis epidemiology worldwide and in Germany.

Indexed as

AbscessBrucella melitensisBrucellosisOvarian DiseasesRare DiseasesAdultAnti-Bacterial AgentsFemaleGermanyHumansAnti-Bacterial AgentsBrucella melitensisDermoid cystEpidemiologyGenito-urinary systemTubo-ovarian abscess

Identifiers

PMID41758455
PMCPMC13323622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.