Evidence map›Paper›PMID 41758290›Full record

Trial reportUpdates in surgery2026

Role of virtual reality exposure before elective day care surgery to reduce patient's distress.

Ludovico Docimo, Claudio Gambardella, Maddalena Paolicelli, Giusiana Nesta, Francesca Fisone, Salvatore Tolone, Roberto Ruggiero, Francesco Saverio Lucido, Giovanni Conzo, Giovanni Cozzolino and 4 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ludovico DocimoDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Claudio GambardellaDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Maddalena PaolicelliDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Giusiana NestaDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Francesca FisoneDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Salvatore ToloneDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Roberto RuggieroDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Francesco Saverio LucidoDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Giovanni ConzoDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Giovanni CozzolinoDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy.
Salvatore GerbinoDepartment of Engineering, University of Campania "L. Vanvitelli", Via Roma 29, 81031, Aversa, CE, Italy.
Francesco CaputoDepartment of Engineering, University of Campania "L. Vanvitelli", Via Roma 29, 81031, Aversa, CE, Italy.
Antimo CardillicchioDepartment of Engineering, University of Campania "L. Vanvitelli", Via Roma 29, 81031, Aversa, CE, Italy.
Simona ParisiDepartment of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia, 80131, Naples, Italy. Simona.parisi@unicampania.it.ORCID http://orcid.org/0000-0001-9974-5106

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preoperative anxiety is a common condition that can negatively impact patient compliance, pain tolerance, and anesthesia management. Traditional pharmacological treatments include sedatives and anxiolytics, but these can cause adverse effects, such as respiratory issues. Non-pharmacological approaches like cognitive-behavioral therapy (CBT), aromatherapy, and music therapy have also been explored but they require pathways of variable duration that may delay surgery. Virtual reality (VR) is emerging as a promising alternative, allowing patients to engage in immersive experiences that distract them from anxiety-inducing stimuli. A prospective randomized controlled trial was conducted to assess the impact of VR on preoperative anxiety and postoperative pain in patients undergoing elective surgery. A total of 355 patients were randomized into two groups: Group A received entertainment videos via VR headset during the preoperative phase, while Group B received standard care. The primary outcome was the change in STAI (State-Trait Anxiety Inventory) scores at baseline, preoperatively, and postoperatively. Secondary outcomes included pain assessment using the Visual Analog Scale (VAS). Results showed no significant difference in baseline anxiety scores between the two groups. However, both preoperative and postoperative STAI scores were significantly lower in the VR group (p = 0.001 and 0.005, respectively). Additionally, 12 h post-surgery, patients in the VR group reported significantly lower pain scores (3.6 ± 1.3 vs. 5.6 ± 1.6, p = 0.001). No significant differences in pain scores were observed at 24 and 48 h post-surgery. VR could represent a useful aid in the management of preoperative anxiety.

Indexed as

Ambulatory Surgical ProceduresAnxietyElective Surgical ProceduresPostoperative PainPreoperative CareVirtual RealityVirtual Reality Exposure TherapyAdultAgedFemaleHumansMaleMiddle AgedPain MeasurementProspective StudiesAnxietyPostoperative painPreoperative managementVirtual reality

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.