Evidence map›Paper›PMID 41758134›Full record

ArticlePacific Symposium on Biocomputing. Pacific Symposium on Biocomputing2026

Scoring Physician Risk Communication in Prostate Cancer Using Large Language Models.

Guillermo Lopez-Garcia, Dongfang Xu, Michael Luu, Renning Zheng, Timothy J Daskivich, Graciela Gonzalez-Hernandez

Abstract read
In one paragraph

Article in Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Guillermo Lopez-GarciaDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Guillermo.LopezGarcia@cshs.org.
Dongfang XuDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Dongfang.Xu@cshs.org.
Michael LuuDepartment of Biostatistics, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Michael.Luu@cshs.org.
Renning ZhengDepartment of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA5Tsinghua Medicine, Tsinghua University Beijing, China, Renning.Zheng@cshs.org.
Timothy J DaskivichDepartment of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Timothy.Daskivich@cshs.org.
Graciela Gonzalez-HernandezDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA, Graciela.GonzalezHernandez@csmc.edu.

Funding

AI Methods for Large Scale Epidemiological Studies using Patient Reports of Medication Adherence and TolerabilityR01LM014731 · NLM · CEDARS-SINAI MEDICAL CENTER · PI GONZALEZ HERNANDEZ, GRACIELA, SHEN, LI · 2025 to 2025
$3.5M
Natural Language Processing Based Consultation Feedback to Improve Patient Decision Making and Physician Risk CommunicationR01CA290559 · NCI · CEDARS-SINAI MEDICAL CENTER · PI TIMOTHY DASKIVICH · 2025 to 2026
$761k
NCI NIH HHS R01 CA290559NLM NIH HHS R01 LM014731
6 · The paper itself

Abstract

Effective risk communication is essential to shared decision-making in prostate cancer care. However, the quality of physician communication of key concepts varies widely in real-world consultations. Manual evaluation of communication is labor-intensive and not scalable. We present a structured, rubric-based framework that uses large language models (LLMs) to automatically score the quality of risk communication in prostate cancer consultations. Using transcripts from 20 clinical visits, we curated and annotated 487 physician-spoken sentences that referenced five key concepts for shared decision-making: cancer prognosis, life expectancy, and three treatment side effects (erectile dysfunction, incontinence, and irritative urinary symptoms). Each sentence was assigned a score from 0 to 5 based on the precision and patient-specificity of communicated risk, using a validated scoring rubric. We modeled this task as five multiclass classification problems and evaluated both finetuned transformer baselines and GPT-4o with rubric-based and chain-of-thought (CoT) prompting. Our best performing approach, which combined rubric-based CoT prompting with few-shot learning, achieved micro averaged F1 scores between 85.0 and 92.0 across domains, outperforming supervised baselines and matching inter-annotator agreement. These findings establish a scalable foundation for AI-driven evaluation of physician-patient communication in oncology and beyond.

Indexed as

CommunicationLarge Language ModelsPhysician-Patient RelationsProstatic NeoplasmsComputational BiologyDecision Making, SharedHumansMalePhysicians

Identifiers

PMID41758134
PMCPMC13598975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.