Evidence map›Paper›PMID 41758064›Full record

ArticleAmerican journal of reproductive immunology (New York, N.Y. : 1989)2026

Enumeration, Phenotyping, and Clinical Associations of Tissue-Resident T Cells in the Ecto- and Endocervix of Women Attending a Colposcopy Clinic.

Aloysious Ssemaganda, Nyambura Kahia, Myo Minn Oo, Dafne Rozenberg, Faisal Nuhu, Naima Jahan, Fran Mulhall, Karen Downing, Bonnie Sandberg, Heather Elands and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of reproductive immunology (New York, N.Y. : 1989), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Tissue-resident memory T cells reshapeFrontiers in immunology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Aloysious SsemagandaDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Nyambura KahiaDepartment of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
Myo Minn OoDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Dafne RozenbergDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Faisal NuhuDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Naima JahanDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Fran MulhallDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Karen DowningDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Bonnie SandbergDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Heather ElandsDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Robyn GroffDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Alon D AltmanDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Christine RobinsonDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Yoav KeynanDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Charles N BernsteinDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-8041-3574
Vanessa PoliquinDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Janilyn ArsenioDepartment of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada.
Lyle R McKinnonDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.

Funding

CIHR IBC-154050
6 · The paper itself

Abstract

problemTissue-resident memory (T METHOD OF STUDY: We used flow cytometry and single cell RNA sequencing (scRNAseq) to characterize T cells isolated from ectocervical biopsies and endocervical cytobrushes collected from women attending a colposcopy clinic in Winnipeg, Canada.

resultsThe ectocervix generally contained a higher frequency and abundance of immune cells and T-cells compared to the endocervix. CD4+ and CD8+ T

conclusionsOur data suggest that T

Indexed as

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCervix UteriMemory T CellsAdultColposcopyFemaleHumansImmunologic MemoryImmunophenotypingMiddle Aged

Identifiers

PMID41758064
PMCPMC12947806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.