ArticleMicrobiology spectrum2026
Targeted next-generation sequencing for comprehensive diagnosis and drug resistance detection in pulmonary and extrapulmonary tuberculosis: a single-center retrospective study.
Jingyi Dai, Qiujing Li, Juan Wan, Fengshuo Sun, Gang Zhou, Meiqiu Yang, Chuanshu Dong, Yao Fang, Lifeng Li, Lin Wang and 1 more
Abstract read
In one paragraphArticle in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Jingyi Dai *Department of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, People's Republic of China.ORCID 0000-0002-9210-8902 Qiujing Li *Department of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, People's Republic of China.ORCID 0009-0005-6817-9240 Juan WanDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, People's Republic of China.
Gang ZhouGenskey Medical Technology Co., Ltd, Beijing, People's Republic of China.
Meiqiu YangDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, People's Republic of China.
Chuanshu DongDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, People's Republic of China.
Yao FangDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, People's Republic of China.
Lifeng LiGenskey Medical Technology Co., Ltd, Beijing, People's Republic of China.
Lin WangDepartment of Medical Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, People's Republic of China.ORCID 0000-0001-8008-6104 Guiming LiuDepartment of Public Laboratory, The Third People's Hospital of Kunming City/Infectious Disease Clinical Medical Center of Yunnan Province, Kunming, Yunnan, People's Republic of China.ORCID 0009-0008-7433-7075 Funding
Clinical Medical Center Scientific Research Project of Yunnan Province 2024YNLCYXZX0205Kunming Science and Technology Bureau 2023-1-NS-007State Key Laboratory of Pathogen and Biosecurity open research project SKLPBS2445Yunnan Province Major Science and Technology Special Plan 202402AA310011
6 · The paper itselfAbstract
Tuberculosis (TB), including drug-resistant forms, is a significant global health issue requiring accurate and rapid diagnostic tools. Traditional diagnostic methods suffer from low sensitivity and slow results, while nucleic acid amplification tests (NAATs) like Xpert MTB/RIF provide faster but incomplete solutions. Targeted next-generation sequencing (tNGS) has the potential to simultaneously detect
Indexed as
High-Throughput Nucleotide SequencingMycobacterium tuberculosisTuberculosis, Multidrug-ResistantTuberculosis, PulmonaryAdultAgedAntitubercular AgentsBronchoalveolar Lavage FluidDrug Resistance, BacterialFemaleHumansMaleMiddle AgedMolecular Diagnostic TechniquesMutationRetrospective StudiesAntitubercular AgentsRifampindiagnostic performancedrug resistancepulmonary and extrapulmonary samplestargeted next-generation sequencingtuberculosis
Identifiers
PMID41757961
PMCPMC13055381
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