Evidence map›Paper›PMID 41757761›Full record

ArticleJournal of digestive diseases

Transcolonic Endoscopic Appendectomy: A Single-Step "Two-In-One" Approach for Recurrent Appendicitis With Appendiceal Orifice Lesions.

Hao Wu, Zhu Kai Chen, Ai Ping Xu, Yuan Chu, Li Zhang, Jing Jing Lian, Tao Chen, Mei Dong Xu

Abstract read
In one paragraph

Article in Journal of digestive diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao WuEndoscopy Center, Shanghai East Hospital, Tongji University, Shanghai, China.
Zhu Kai ChenEndoscopy Center, Shanghai East Hospital, Tongji University, Shanghai, China.
Ai Ping XuEndoscopy Center, Shanghai East Hospital, Tongji University, Shanghai, China.
Yuan ChuEndoscopy Center, Shanghai East Hospital, Tongji University, Shanghai, China.
Li ZhangDepartment of Pathology, Shanghai East Hospital, Tongji University, Shanghai, China.
Jing Jing LianEndoscopy Center, Shanghai East Hospital, Tongji University, Shanghai, China.
Tao ChenEndoscopy Center, Shanghai East Hospital, Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0002-8016-9732
Mei Dong XuEndoscopy Center, Shanghai East Hospital, Tongji University, Shanghai, China.

Funding

Fundamental Research Funds for the Central Universities 22120240372 (T.C.)Key Disciplines Group Construction Project of Shanghai Pudong New Area Health Commission PWZxq2022-06 (M.D.X.)Key Disciplines Group ConstructionProject of Shanghai Pudong New Area Health Commission PWZxq2022-06 (M.D.X.)Medical Discipline Construction Project of Pudong Health Committee of Shanghai 2024-PWXZ-007 (M.D.X.)Medical Discipline Construction Project of Pudong Health Committee of Shanghai 2025PDWSYCBJ-01 (T.C.)National Natural Science Foundation of China 82372921 (T.C.)National Natural Science Foundation of China 82473094 (M.D.X.)Shanghai Municipal Health Commission 2024ZDXK0001 (M.D.X.)
6 · The paper itself

Abstract

objectivesAppendiceal orifice lesions are occasionally detected during colonoscopy in patients with recurrent appendicitis. Conventional surgery with partial cecal resection may cause unnecessary trauma. Transcolonic endoscopic appendectomy (TEA) has been proposed as a minimally invasive alternative. We aimed to evaluate the feasibility, safety, and efficacy of transcolonic endoscopic appendectomy and to compare through-the-scope twin clips (TTS-TC) combined with metal clips versus metal clips alone for defect closure.

methodsTwenty patients with recurrent appendicitis and no prior abdominal surgery who underwent transcolonic endoscopic appendectomy between December 2020 and December 2024 were included. Clinical and pathological variables, procedural parameters, and follow-up outcomes were analyzed. TTS-TC plus metal clips and metal clips alone for defect closure were compared.

resultsAll procedures were technically and clinically successful. Postoperative time to resume diet and length of hospital stay were 4.05 and 6.40 days, respectively. TTS-TC combined with metal clips reduced suture time (18 min [interquartile range {IQR} 15.5-20 min] vs. 25 min [IQR 20-30 min]), procedure time (85 min [IQR 72.5-92 min] vs. 115 min [IQR 110-124 min]), and number of clips used (7 [IQR 6.5-8] vs. 8 [IQR 7-9]) compared with metal clips alone. No adverse events were reported. Colonoscopy performed at 3 months post-procedure showed no residual lesions or recurrence.

conclusionsTEA is a feasible, safe, and effective approach for recurrent appendicitis with orifice lesions. It provides a minimally invasive dual-benefit strategy and can be facilitated by a novel closure method to streamline the procedure.

Indexed as

AppendectomyAppendicitisAppendixColonoscopyAdultFeasibility StudiesFemaleHumansLength of StayMaleMiddle AgedOperative TimeRecurrenceRetrospective StudiesSurgical InstrumentsTreatment Outcomeappendiceal diseasesappendicitisendoscopic clip techniquesendoscopygastrointestinalminimally invasive surgical procedures

Identifiers

PMID41757761
PMCPMC13097961

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.