Evidence map›Paper›PMID 41757604›Full record

ReviewAnalytical chemistry2026

Evanescent Wave-Based Photonic Biosensors for the Design and Evaluation of Advanced Cancer Immunotherapies.

César S Huertas, Laura M Lechuga, Maria Soler

Abstract readReview
In one paragraph

Review in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

César S HuertasIntegrated Photonics and Applications Centre (InPAC), School of Engineering, RMIT University, Melbourne 3001, Australia.
Laura M LechugaNanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, 08193 Bellaterra (Barcelona), Spain.ORCID 0000-0001-5187-5358
Maria SolerNanobiosensors and Bioanalytical Applications Group (NanoB2A), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and BIST, 08193 Bellaterra (Barcelona), Spain.ORCID 0000-0001-7232-2277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Personalized immunotherapies hold great promise for correcting cellular dysfunction, inhibiting tumor growth, and even achieving durable cancer eradication. However, conventional analytical methods used to design and evaluate immunotherapies often fall short as they typically cannot monitor cell activity in real time, lack multiplexed capabilities for rapid screening, and require complex sample preparation. These limitations impede a full understanding of the dynamic immune responses that drive therapeutic outcomes. Label-free optical biosensors based on evanescent wave interactions provide a compelling alternative, enabling sensitive, noninvasive, and high-resolution analysis of cellular regulation, signaling, and therapy-induced molecular changes. In this perspective, we highlight recent advances in optical biosensor technologies for molecular and cell analysis and explore their potential to accelerate the development, optimization, and precision application of next-generation immunotherapies.

Indexed as

Biosensing TechniquesImmunotherapyNeoplasmsPhotonsAnimalsHumans

Identifiers

PMID41757604
PMCPMC12980497

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.