Evidence map›Paper›PMID 41757477›Full record

ArticleTurk gogus kalp damar cerrahisi dergisi2026

Surgical outcomes of left atrial resection for lung cancer: A single-center study.

Aysun Kosif, Elçin Ersöz Köse, Meltem Ağca, Sevinç Çıtak, Rıza Serdar Evman, Abidin Levent Alpay, Volkan Baysungur

Abstract read
In one paragraph

Article in Turk gogus kalp damar cerrahisi dergisi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Aysun KosifDepartment of Thoracic Surgery, University of Health Sciences Türkiye, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0002-9490-9826
Elçin Ersöz KöseDepartment of Thoracic Surgery, University of Health Sciences Türkiye, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0002-6097-2835
Meltem AğcaDepartment of Chest Disease, University of Health Sciences Türkiye, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0001-9694-7909
Sevinç ÇıtakDepartment of Thoracic Surgery, University of Health Sciences Türkiye, Koşuyolu High Specialization Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0002-9983-3330
Rıza Serdar EvmanDepartment of Thoracic Surgery, University of Health Sciences Türkiye, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0002-1672-966X
Abidin Levent AlpayClinic of Thoracic Surgery, Medicana Ataköy Hospital, İstanbul, Türkiye.ORCID 0000-0001-8872-166X
Volkan BaysungurDepartment of Thoracic Surgery, University of Health Sciences Türkiye, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0003-1053-1051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Left atrial invasion is classified as T4 non-small cell lung cancer (NSCLC). Surgical outcomes vary in selected patients. This study presents outcomes of left atrial resection at our center. Methods: Between August 2008 and May 2022, surgical outcomes of 41 NSCLC patients with left atrial invasion were retrospectively analyzed. Demographics, tumor characteristics, surgical procedures (pneumonectomy, lobectomy), nodal status (N0, N1, N2), and margin status (complete [R0], incomplete [R1]) were recorded. In-hospital mortality, morbidity, and long-term survival were evaluated. Cox proportional hazards regression model was used to assess all-cause mortality. Results: Mean age was 61.8 (±11.6) years, and 90.2% of patients were male. Median tumor diameter was 4.5 cm (interquartile range, 3.5-5.5 cm), 53.7% of tumors were right-sided. Squamous cell carcinoma was the predominant subtype (78%). Pathological nodal status was N0 in 25 patients and N1/N2 in 8 patients each. Complete resection was achieved in 35 patients (85.4%). In-hospital mortality was 4.8%, and long-term mortality was 70.8%. Median overall survival was 2.11 years (95% confidence interval [CI], 1.17-3.05). Multivariate Cox regression analysis identified N2 disease and incomplete (R1) resection as independent predictors of poor survival (N2: hazard ratio [HR], 3.7; 95% CI, 1.22-11.19; p=0.021; incomplete R1 resection: HR, 4.46; 95% CI, 1.42-14; p=0.010). Age (≥65 vs. <65), smoking, tumor size, side of surgery and neoadjuvant therapy were not significant in either univariate or multivariate analyses (all p>0.05). Conclusion: In NSCLC with left atrial invasion, surgery is feasible in selected patients, and long-term survival depends on excluding N2 disease and achieving complete resection.

Indexed as

Left atrialnon-small cell lung cancersurgical treatment

Identifiers

PMID41757477
PMCPMC13051729

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