Evidence map›Paper›PMID 41757457›Full record

ArticleRNA biology2026

Sequence and ionic requirements of pUG fold quadruplexes.

Saeed Roschdi, Takuma Kume, Riley J Petersen, Abby McCann, Cristian A Escobar Bravo, Anika Richard, Samuel Butcher

Abstract read
In one paragraph

Article in RNA biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Perspective - RNA Dynamics Today and Tomorrow.Journal of molecular biology · 2026
    Review
  4. Article
  5. PXL: a Nucleic Acid-Binding Module of Promyelocytic Leukemia Protein.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Saeed RoschdiDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-6360-6868
Takuma KumeDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-0448-1991
Riley J PetersenDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-3598-0507
Abby McCannDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.
Cristian A Escobar BravoDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-4607-2996
Anika RichardDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.
Samuel ButcherDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-6343-6643

Funding

Biophysical investigations of RNA complexes essential for gene expressionR35GM118131 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Samuel E Butcher · 2016 to 2026
$5.1M
NIGMS NIH HHS R35 GM118131
6 · The paper itself

Abstract

Poly(UG) repeats or pUG RNAs can fold into a left-handed parallel quadruplex, the pUG fold. The pUG fold directs the epigenetic amplification of RNAi in

Indexed as

G-QuadruplexesPoly URNA FoldingAnimalsBase SequenceCaenorhabditis elegansNucleic Acid ConformationPotassiumThermodynamicsPoly UPotassiumpUG foldquadruplexRNA foldingRNAiRNA structure

Identifiers

PMID41757457
PMCPMC12962679

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.