Evidence map›Paper›PMID 41757358›Full record

Article... International Conference on Learning Representations2022

Explanations of Black-Box Models based on Directional Feature Interactions.

Aria Masoomi, Davin Hill, Zhonghui Xu, Craig P Hersh, Edwin K Silverman, Peter J Castaldi, Stratis Ioannidis, Jennifer Dy

Abstract read
In one paragraph

Article in ... International Conference on Learning Representations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aria MasoomiNortheastern University, Department of Electrical and Computer Engineering, Boston, MA, USA.
Davin HillNortheastern University, Department of Electrical and Computer Engineering, Boston, MA, USA.
Zhonghui XuBrigham and Women's Hospital, Channing Division of Network Medicine, Boston, MA, USA.
Craig P HershBrigham and Women's Hospital, Channing Division of Network Medicine, Boston, MA, USA.
Edwin K SilvermanBrigham and Women's Hospital, Channing Division of Network Medicine, Boston, MA, USA.
Peter J CastaldiBrigham and Women's Hospital, Channing Division of Network Medicine, Boston, MA, USA.
Stratis IoannidisNortheastern University, Department of Electrical and Computer Engineering, Boston, MA, USA.
Jennifer DyNortheastern University, Department of Electrical and Computer Engineering, Boston, MA, USA.

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASEST32HL007427 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI DAWN L DEMEO, Edwin K Silverman · 1985 to 2026
$13.6M
Using Integrative Genomics To Identify and Characterize Emphysema-Associated eQTLR01HL124233 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2014 to 2024
$7.1M
Prospective Health Outcomes and Inflammatory Biomarkers Associated with e-Cigarette UseR01HL147326 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2019 to 2021
$1.5M
NHLBI NIH HHS R01 HL124233NHLBI NIH HHS R01 HL147326NHLBI NIH HHS T32 HL007427NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

As machine learning algorithms are deployed ubiquitously to a variety of domains, it is imperative to make these often black-box models transparent. Several recent works explain black-box models by capturing the most influential features for prediction per instance; such explanation methods are univariate, as they characterize importance per feature. We extend univariate explanation to a higher-order; this enhances explainability, as bivariate methods can capture feature interactions in black-box models, represented as a directed graph. Analyzing this graph enables us to discover groups of features that are equally important (i.e., interchangeable), while the notion of directionality allows us to identify the most influential features. We apply our bivariate method on Shapley value explanations, and experimentally demonstrate the ability of directional explanations to discover feature interactions. We show the superiority of our method against state-of-the-art on CIFAR10, IMDB, Census, Divorce, Drug, and gene data.

Identifiers

PMID41757358
PMCPMC12933520

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.