Evidence map›Paper›PMID 41757100›Full record

ArticlebioRxiv : the preprint server for biology2026

Injury Causes Altered Metabolism including O

Aidan J Gregory, Priyanka P Brahmachary, Molly E Piazza, William S Rockwell, Erik Myers, Mark Greenwood, Ross P Carlson, Ronald K June

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aidan J GregoryDepartment of Mechanical & Industrial Engineering, Montana State University, Bozeman, MT.
Priyanka P BrahmacharyDepartment of Mechanical & Industrial Engineering, Montana State University, Bozeman, MT.
Molly E PiazzaDepartment of Mechanical & Industrial Engineering, Montana State University, Bozeman, MT.
William S RockwellDepartment of Mechanical & Industrial Engineering, Montana State University, Bozeman, MT.
Erik MyersDepartment of Mechanical & Industrial Engineering, Montana State University, Bozeman, MT.
Mark GreenwoodDepartment of Mathematical Sciences, Montana State University, Bozeman, MT.
Ross P CarlsonDepartment of Chemical & Biological Engineering, Montana State University, Bozeman, MT.
Ronald K JuneDepartment of Mechanical & Industrial Engineering, Montana State University, Bozeman, MT.ORCID 0000-0003-0752-4109

Funding

Role of Glucose metabolism in Chondrocyte MechanotransductionR01AR073964 · NIAMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI JUNE, RONALD KENT · 2019 to 2024
$2.4M
Metabolomic Profiling to Identify Candidate Biomarker Profiles and Molecular Endotypes for OsteoarthritisR01AR081489 · NIAMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Ronald Kent June · 2023 to 2026
$1.8M
NIAMS NIH HHS R01 AR073964NIAMS NIH HHS R01 AR081489
6 · The paper itself

Abstract

Traumatic joint injuries both disrupt chondrocyte metabolism and increase the risk for post-traumatic osteoarthritis. Yet the relationships between trauma, altered metabolism, and cartilage degradation remains unclear. This study compares the metabolic responses of bovine (normal) and osteoarthritic (OA) chondrocytes to physiological and injurious mechanical stimuli under normoxic (20% O

Indexed as

chondrocytehypoxiainjurymetabolismmetabolomics

Identifiers

PMID41757100
PMCPMC12934726

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.