ArticlebioRxiv : the preprint server for biology2026
Generation and characterization of a novel MHC-II tetramer for tracking and characterization of toxin B-specific CD4
Jeffrey R Maslanka, Qianxuan She, Kathleen S Krauss, Emily N Konopka, Nile U Bayard, Jennifer Londregan, Mohamad-Gabriel Alameh, Laurence C Eisenlohr, Michele A Kutzler, Joseph P Zackular and 1 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
11 authors.
Jeffrey R MaslankaDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-6982-5946 Qianxuan SheDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia; Philadelphia, PA, USA.
Kathleen S KraussDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia; Philadelphia, PA, USA.ORCID 0000-0001-9432-6623 Emily N KonopkaDrexel University College of Medicine, Department of Medicine. Philadelphia, PA, USA.
Nile U BayardDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia; Philadelphia, PA, USA.
Jennifer LondreganImmunology Graduate Group, University of Pennsylvania, Philadelphia, PA, USA.
Mohamad-Gabriel AlamehDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia; Philadelphia, PA, USA.
Laurence C EisenlohrDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia; Philadelphia, PA, USA.
Michele A KutzlerDrexel University College of Medicine, Department of Medicine. Philadelphia, PA, USA.
Joseph P ZackularDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia; Philadelphia, PA, USA.
Michael C AbtDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-7351-2061 Funding
cGMP Manufacture, Fill-Finish, Release, Analytical and Stability Testing and Stability Program of a Nanoparticle Based HIV Envelope Vaccine75N93022D00005 · NIAID · INTERNATIONAL AIDS VACCINE INITIATIVE · PI HASSELL, THOMAS · 2022 to 2025
$8.0MProject 3: Defining adaptive immune interactions that shape Clostridioides difficile infectionU19AI174998 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI DREW WEISSMAN · 2023 to 2026
$7.6MTask Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00005 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2020 to 2025
$5.1MInvestigating Immune-Microbiome interactions during treatment of Clostridioides difficile with fecal microbiome transplantationR01AI158830 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ABT, MICHAEL C. · 2021 to 2025
$2.4MNHLBI NIH HHS 75N92020D00005NIAID NIH HHS 75N93022D00005NIAID NIH HHS R01 AI158830NIAID NIH HHS U19 AI174998NIDA NIH HHS 75N95020D00005NIH HHS 75N93023D00005NIH HHS 75N99020D00005
6 · The paper itselfAbstract
The gastrointestinal pathogen
Indexed as
CD4+ T cell epitopesC. difficilemRNA-LNPtetramerToxin B
Identifiers
PMID41757099
PMCPMC12934791
What OpenQuestion holds
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