Evidence map›Paper›PMID 41757077›Full record

ArticlebioRxiv : the preprint server for biology2026

A hypoxia-sensitive medullary nucleus modulates cerebral blood flow via a disynaptic pathway to cortex.

Karishma Chhabria, Jacob Duckworth, Pantong Yao, Arash Fassihi-Zakeri, David Kleinfeld

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karishma ChhabriaDepartment of Physics, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-8570-0871
Jacob DuckworthDepartment of Physics, University of California, San Diego, La Jolla, CA, USA.ORCID 0009-0003-7447-9819
Pantong YaoNeuroscience Graduate Program, University of California, San Diego, La Jolla, CA, USA.
Arash Fassihi-ZakeriDepartment of Physics, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-0590-918X
David KleinfeldDepartment of Physics, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-9797-4722

Funding

Project 4U19NS123717 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI DEVOR, ANNA · 2021 to 2025
$13.4M
Imaging the molecular constituents of the brain vasculature and lymphatic connectomeU24EB028942 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KLEINFELD, DAVID · 2019 to 2024
$1.8M
NIBIB NIH HHS U24 EB028942NINDS NIH HHS U19 NS123717
6 · The paper itself

Abstract

The RVLM (rostral ventral lateral medulla) region of the brainstem is implicated as a controller of both systemic and cerebral blood flow (CBF). Past studies leave open the question of how the RVLM stabilizes CBF in awake animals. Here, we focus on CBF regulation by the adenergic subpopulation of RVLM neurons (RVLM

Identifiers

PMID41757077
PMCPMC12934959

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.