Evidence map›Paper›PMID 41757038›Full record

ArticlebioRxiv : the preprint server for biology2026

AP-3 and the V-ATPase Modulate CTP Synthase Assembly Through Spatial Association at the Yeast Vacuole.

Michaela McCright, Mitchell Leih, Ayla Nack, Cortney G Angers, Alexey J Merz, Greg Odorizzi

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Michaela McCrightDepartment of Molecular Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.ORCID 0009-0007-7806-2366
Mitchell LeihDepartment of Molecular Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.ORCID 0000-0002-5927-6154
Ayla NackDepartment of Molecular Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.
Cortney G AngersDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Alexey J MerzDepartment of Biochemistry, University of Washington, Seattle, WA 98195.ORCID 0000-0003-2177-6492
Greg OdorizziDepartment of Molecular Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.ORCID 0000-0002-1143-1098

Funding

Membrane trafficking to lysosomeshttps://apps.era.nih.gov/gmii/manage/view.era?applId=11030651#R35GM149202 · NIGMS · UNIVERSITY OF COLORADO · PI CHARLES G ODORIZZI · 2023 to 2026
$2.2M
NIGMS NIH HHS R35 GM149202
6 · The paper itself

Abstract

The compartmentalization of metabolic enzymes into membraneless filaments termed cytoophidia represents a conserved regulatory mechanism, exemplified by cytidine triphosphate synthase (CTP synthase). CTP synthase assembles into pH-sensitive cytoophidia in the cytosol. In

Indexed as

AP-3CTP synthasecytoophidiametabolic enzyme compartmentalizationpH regulationspatial organizationvacuolar H -ATPasevacuole

Identifiers

PMID41757038
PMCPMC12934586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.