Evidence map›Paper›PMID 41756967›Full record

ArticlebioRxiv : the preprint server for biology2026

Hypoxic stress granules trigger immunogenic dormancy in lung cancer.

Matthew G Smith, Alexis Rebecca Ramos, Heena Panchal, N Harun Cerkezi, Cassandra Garcia, Lynn Spruce, Hossein Fazalinia, Leonard B Maggi, Adam W Mailloux

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthew G SmithDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA.
Alexis Rebecca RamosDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA.
Heena PanchalDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA.
N Harun CerkeziDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA.
Cassandra GarciaDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA.
Lynn SpruceProteomics Core Facility, Children's Hospital of Philadelphia, Philadelphia, PA.
Hossein FazaliniaProteomics Core Facility, Children's Hospital of Philadelphia, Philadelphia, PA.
Leonard B MaggiDepartment of Medicine, Division of Molecular Oncology, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0003-0138-0984
Adam W MaillouxDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA.ORCID 0000-0002-4563-6489

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Jon C.D. Houtman · 2000 to 2026
$70.0M
Autohistomagnetic Isolation of Tumor-reactive T-cellsR21CA214285 · NCI · UNIVERSITY OF IOWA · PI MAILLOUX, ADAM WILLIAM · 2018 to 2020
$638k
NCI NIH HHS P30 CA086862NCI NIH HHS R21 CA214285
6 · The paper itself

Abstract

Induction of the MHC class I antigen processing and presentation pathway (C1APP) is a critical part of the IFN-γ response necessary for effective cytotoxic immunity against tumors of epithelial origin

Identifiers

PMID41756967
PMCPMC12934956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.