ArticlebioRxiv : the preprint server for biology2026
Glycolytic Specialization Shapes Neuronal Physiology and Function
Aaron D Wolfe, Longgang Niu, L Safak Yilmaz, Snusha Ravikumar, Matthew Thomas, Albertha J M Walhout, Zhao-Wen Wang, Richard H Goodman, Daniel A Colón-Ramos
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Aaron D WolfeDepartments of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, CT 06536, USA.ORCID 0000-0002-4926-5064 Longgang NiuDepartment of Neuroscience, University of Connecticut Health Center, Farmington, CT 06030, USA.
L Safak YilmazDepartment of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.
Snusha RavikumarDepartments of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, CT 06536, USA.
Matthew ThomasDepartments of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, CT 06536, USA.
Albertha J M WalhoutDepartment of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.ORCID 0000-0001-5587-3608 Zhao-Wen WangDepartment of Neuroscience, University of Connecticut Health Center, Farmington, CT 06030, USA.
Richard H GoodmanDepartments of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, CT 06536, USA.
Daniel A Colón-RamosDepartments of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, CT 06536, USA.ORCID 0000-0003-0223-7717 Funding
Transcription networks in C elegans organogenesisR01DK068429 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI A. J. Marian Walhout · 2005 to 2026
$10.9MGene regulatory and metabolic network structure, function and evolutionR35GM122502 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI A. J. Marian Walhout · 2017 to 2026
$8.3MEnhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5MSynaptic function of BK channel-interacting proteinsR01MH085927 · NIMH · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI ZHAO-WEN WANG · 2010 to 2026
$6.7MExamination of the cell biology of the synapse and behaviorR35NS132156 · NINDS · YALE UNIVERSITY · PI DANIEL A COLON-RAMOS · 2023 to 2026
$4.6MCellular and molecular mechanisms that temporally and spatially restrict synapticR01NS076558 · NINDS · YALE UNIVERSITY · PI COLON-RAMOS, DANIEL A · 2012 to 2022
$4.1MAdaptive glycolysis as a regulator of neuronal function and declineK99AG083129 · NIA · YALE UNIVERSITY · PI WOLFE, AARON · 2023 to 2024
$252kNIA NIH HHS K99 AG083129NIDDK NIH HHS R01 DK068429NIGMS NIH HHS R35 GM122502NIH HHS P40 OD010440NIMH NIH HHS R01 MH085927NINDS NIH HHS R01 NS076558NINDS NIH HHS R35 NS132156
6 · The paper itselfAbstract
Neurons perform diverse functions that impose distinct energetic demands, but how energy-metabolic pathways are matched to these functions
Identifiers
PMID41756937
PMCPMC12934643
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