Evidence map›Paper›PMID 41756747›Full record

ArticlePulmonary circulation2026

Efficacy and Safety of Low-Dose Prolonged Infusion Thrombolysis With rt-PA for Acute Intermediate-High Risk Pulmonary Embolism.

Wenxiang Qi, Maofeng Gong, Hao Huang, Yangyi Zhou, Haobo Su

Abstract read
In one paragraph

Article in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenxiang QiDepartment of Interventional and Vascular Radiology, Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu China.
Maofeng GongDepartment of Interventional and Vascular Radiology, Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu China.
Hao HuangDepartment of Interventional and Vascular Radiology, Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu China.
Yangyi ZhouDepartment of Interventional and Vascular Radiology, Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu China.
Haobo SuDepartment of Interventional and Vascular Radiology, Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu China.ORCID https://orcid.org/0009-0008-0576-1884

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombolytic therapy alleviates pulmonary embolism (PE) symptoms rapidly but increases bleeding risk, with no consistent consensus on acute intermediate-high risk PE. This study evaluated the efficacy and safety of low-dose prolonged infusion thrombolysis for acute intermediate-high risk PE to provide a safer clinical option. A total of 120 patients were collected and divided into anticoagulant (Group A,

Indexed as

alteplaseanticoagulation therapypulmonary embolismsystemic thrombolytic therapy

Identifiers

PMID41756747
PMCPMC12933405

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.