Evidence map›Paper›PMID 41756685›Full record

ArticleJournal of nursing management2026

Associations Between Night Shifts and Comorbid Depressive-Anxiety Symptoms Among Chinese Nurses: Indirect Associations via Sleep Quality and Duration.

Chenhao Zhang, Jiali Zhou, Yi Zhou, Siyu Zhu, Weidi Sun, Shiyi Shan, Zeyu Luo, Denan Jiang, Lili Yang, Peige Song

Abstract read
In one paragraph

Article in Journal of nursing management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chenhao ZhangCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.
Jiali ZhouCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.ORCID https://orcid.org/0009-0004-9693-9801
Yi ZhouCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.
Siyu ZhuCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.
Weidi SunCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.
Shiyi ShanCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.
Zeyu LuoCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.
Denan JiangCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.
Lili YangDepartment of Nursing, The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China, zju.edu.cn.ORCID https://orcid.org/0000-0002-4587-1438
Peige SongCenter of Clinical Big Data and Analytics of the Second Affiliated Hospital and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China, zju.edu.cn.ORCID https://orcid.org/0000-0002-0196-9759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Irregular sleep, frequently resulting from night shifts, is associated with various mental health issues. However, the specific associations among these factors remain unclear. This study aimed to investigate the associations of night shift frequency with depressive, anxiety, and comorbid depressive-anxiety symptoms and to estimate the indirect associations through sleep quality and sleep duration. Methods: A cross-sectional study was conducted among nurses in seven hospitals in Zhejiang Province in 2023. A self-administered questionnaire was utilized to collect sociodemographic, work-related, lifestyle, and mental health information. Multivariable logistic regression models were used to examine the associations of night shift frequency, sleep duration, sleep quality, and mental health outcomes. Additionally, we used a mediation analysis to estimate indirect effects through sleep quality and sleep duration. Results: A total of 2037 nurses were included in the study. Compared to low-frequency night shifts, high-frequency night shifts were significantly associated with higher odds of depressive symptoms (odds ratio [OR] = 1.46, 95% confidence interval [CI] = 1.20-1.77), anxiety symptoms (OR = 1.29, 95% CI = 1.06-1.58), and comorbid depressive-anxiety symptoms (OR = 1.34, 95% CI = 1.09-1.65). The statistical indirect association via sleep quality accounted for 19.5%, 25.9%, and 19.0% of the total association for depressive, anxiety, and comorbid depressive-anxiety symptoms, respectively. The indirect effect through sleep duration was not statistically significant. Conclusions: In this cross-sectional study, a higher frequency of night shifts was significantly associated with poorer mental health outcomes among Chinese nurses, with sleep quality serving as a statistical mediator. These findings suggest that optimizing shift scheduling, enhancing institutional support for sleep recovery, and integrating sleep quality monitoring into occupational health policies may be effective strategies to promote nurse well-being. This study provides empirical evidence to inform nursing management practices and health workforce policy.

Indexed as

AnxietyDepressionNursesSleep QualityWork Schedule ToleranceAdultChinaComorbidityCross-Sectional StudiesEast Asian PeopleFemaleHumansLogistic ModelsMaleMiddle AgedSleep Durationanxietycomorbid symptomsdepressionmediation analysisshift schedulingsleep quality

Identifiers

PMID41756685
PMCPMC12932965

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.