ArticleFrontiers in plant science2026
Integrated metabolomic and transcriptomic analysis of the mechanism underlying leaf variegation in
Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors.
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Abstract
Introduction: Methods: This study was performed with the use of two leaf phenotypes [Yellow area of variegated leaves (YS) and Green area of variegated leaves (GS)] of Results: Metabolomic analysis identified 4,036 common metabolites in GS and YS samples, with major enrichment in the flavonoid biosynthesis pathway. Secondary classification of this pathway indicated that flavonoids had the highest content. Further comparison of the expression levels of key metabolites revealed that the accumulation patterns of neohesperidin, taxifolin, naringenin, and xanthohumol in YS were all higher than those in GS, with naringenin showing the most significant difference, suggesting that it might be the core metabolite regulating leaf spot formation. According to subsequent transcriptome sequencing, 5,252 DEGs were screened out from the YS and GS samples, which were mainly enriched in flavonoid biosynthesis phenylpropanoid biosynthesis and other pathways. qRT-PCR presented the highest expression level in chalcone synthase ( Discussion: This study identifies the core intrinsic regulatory mechanism underlying leaf variegation in
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