Evidence map›Paper›PMID 41756462›Full record

ArticleResearch square2026

Individual and structural benefits, challenges, and strategies for integrating medication assistance treatment and antiretroviral services for persons living with HIV who use drugs in Dar es Salaam, Tanzania.

Dorothy Mushi, Peter Sakejo, Magreat Somba, David Huh, Deepa Rao, Sylvia Kaaya

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorothy MushiMuhimbili University of Health and Allied Sciences.
Peter SakejoMuhimbili University of Health and Allied Sciences.
Magreat SombaIfakara Health Institute.
David HuhUniversity of Washington.
Deepa RaoUniversity of Washington.
Sylvia KaayaMuhimbili University of Health and Allied Sciences.

Funding

University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)P30MH123248 · NIMH · UNIVERSITY OF WASHINGTON · PI CHWASTIAK, LYDIA ANN · 2021 to 2024
$5.8M
NIMH NIH HHS P30 MH123248
6 · The paper itself

Abstract

Background: People who use drugs (PWUDs) have an increased risk of acquiring and transmitting bloodborne diseases, including HIV, hepatitis B and C virus. To manage HIV among people who use drugs and live with HIV (PUD-LWH), health services provide integrated Medication-Assisted and Antiretroviral Treatment Services (IMAT services). Although the IMAT comprehensive care package includes biological, social, and psychological interventions, PUD-LWH's retention in care is suboptimal. A formative needs assessment collected qualitative information to inform adaptation for PUD-LWH of an evidence-based peer-led group psychosocial intervention that showed good clinical and psychosocial outcomes in people living with HIV. Methods: We conducted in-depth interviews with 22 PUD-LWH to understand users' experiences with IMAT services. Healthcare providers (n=6) also participated. Thematic areas explored included perceptions of how the IMAT services process met users' needs, experiences when attending IMAT services, including perceived benefits and challenges, and proposed strategies to overcome reported difficulties. Narrative data were analyzed using thematic analysis. Results: PUD-LWH perceived themselves as physically and mentally stable and acknowledged that IMAT had helped them re-integrate with families. Enacted stigma, out-of-pocket healthcare expenses, and limited time with healthcare providers due to an overburdened IMAT service were challenges to maintaining adherence to IMAT clinic visits and ART medication use. Participants proposed strategies to continue building awareness of IMAT services, reduce enacted stigma related to drug use, enhance client psychosocial care, facilitate the provision of skills for improving income generation for PUD-LWH, and increase the number of IMAT healthcare providers. Conclusions: This formative study reveals individual, family, and community-level facilitators and barriers to accessing and using IMAT services and IMAT services-based structural challenges. IMAT services clients by suggesting strategies to overcome structural challenges.

Indexed as

individual and structural challenges and benefitsmedication assistance treatmentpersons living with HIV who use drugs

Identifiers

PMID41756462
PMCPMC12935000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.