Evidence map›Paper›PMID 41756248›Full record

ArticleResuscitation plus2026

Impact of resuscitation-trained healthcare workforce availability on neonatal asphyxia mortality: a population-based study.

Mandira D Kawakami, Adriana Sanudo, Ana Sílvia S Marinonio, Kelsy N Areco, Rita de Cássia X Balda, Milton H Miyoshi, Daniela T Costa-Nobre, Tulio Konstantyner, Carina N Vieira E Oliveira, Paulo Bandiera-Paiva and 6 more

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mandira D KawakamiEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Adriana SanudoEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Ana Sílvia S MarinonioEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Kelsy N ArecoEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Rita de Cássia X BaldaEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Milton H MiyoshiEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Daniela T Costa-NobreEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Tulio KonstantynerEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Carina N Vieira E OliveiraEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Paulo Bandiera-PaivaEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Rosa M V FreitasFundação Sistema Estadual de Análise de Dados, Brazil.
Mônica L P TeixeiraFundação Sistema Estadual de Análise de Dados, Brazil.
Bernadette WaldvogelFundação Sistema Estadual de Análise de Dados, Brazil.
Carlos Roberto V KifferEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Maria Fernanda de AlmeidaEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.
Ruth GuinsburgEscola Paulista de Medicina - Universidade Federal de São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intrapartum events cause approximately 900,000 neonatal deaths annually worldwide. This study investigated whether the number of healthcare providers trained in resuscitation at the municipal level is associated with decreased neonatal mortality due to perinatal asphyxia. Methods: This population-based study analyzed neonatal deaths with birth weight ≥1500 g without congenital anomalies in São Paulo State, Brazil (2011-2020). Deaths were classified as asphyxia-associated when ICD-10 codes indicating intrauterine hypoxia, birth asphyxia, or neonatal meconium aspiration appeared on any line of death certificates. Temporal trends of neonatal mortality rate associated with perinatal asphyxia (Asphyxia-NMR) and density of Brazilian Neonatal Resuscitation Program (NRP) trained professionals per thousand live births across the 645 municipalities of the State were analyzed using Prais-Winsten regression. A multilevel mixed-effects logistic regression included three hierarchical levels (newborns, municipalities, regional health districts), adjusting for maternal age, prenatal visits, delivery mode, newborn sex, NRP-trained professional density, Gross Domestic Product (log-transformed), and year of birth. Results: Among 6,044,527 live births, 2527 neonatal deaths met inclusion criteria. Asphyxia-NMR declined from 0.43‰ (2011) to 0.31‰ (2020), an annual reduction of 3.84% (95% CI: 0.46-7.10%). The density of NRP-trained professionals rose from 1.67‰ to 35.78‰, an annual increase of 39.97% (95%CI: 24.50-57.35%). Having ≥7 trained professionals per thousand live births decreased the odds of asphyxia-associated neonatal deaths (OR 0.88; 95%CI: 0.80-0.97). Conclusion: Greater availability of healthcare professionals trained in neonatal resuscitation was independently associated with lower neonatal mortality associated with asphyxia, after adjustment for biological, economic, and regional factors.

Indexed as

Healthcare professionalsNeonatal mortalityNewborn infantPerinatal asphyxiaResuscitation

Identifiers

PMID41756248
PMCPMC12933822

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.