ArticleSudanese journal of paediatrics2025
Prevalence and predictors of microalbuminuria and autoimmune comorbidities in children and adolescents with type 1 diabetes mellitus in Saudi Arabia: a retrospective cohort study.
Article in Sudanese journal of paediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Type 1 diabetes mellitus (T1DM) in children is associated with long-term microvascular complications, including diabetic nephropathy, often presenting as microalbuminuria (MA). In parallel, autoimmune comorbidities are prevalent due to shared immunogenetic mechanisms. However, regional data on the co-prevalence of MA and autoimmune disorders in the Saudi pediatric population are limited. The present study aims to determine the prevalence and predictors of microalbuminuria and autoimmune comorbidities in children and adolescents with T1DM in Saudi Arabia. A retrospective cohort study was conducted at King Abdulaziz Medical City, Jeddah, involving 595 pediatric patients with T1DM. Data extracted included demographics, diabetes characteristics, and duodenal biopsy outcomes. Descriptive and multivariate analysis were conducted. Microalbuminuria was present in 8.9% of patients. HbA1c was significantly higher in patients with MA (mean 9.8% vs. 8.9%,
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