ArticleOpen forum infectious diseases2026
Frequent Participation in Ryan White Services Improves Time to Human Immunodeficiency Virus (HIV) Viral Suppression Among People With HIV Monoinfection and People With Hepatitis C Virus (HCV) Coinfection in Philadelphia.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Hepatitis C virus (HCV) coinfection is associated with poor health outcomes for persons with human immunodeficiency virus (HIV). Although higher HIV viral suppression rates have been reported among people with HIV who participate in Ryan White services, studies have not assessed effects on HCV coinfection. Methods: We used Philadelphia's routine HIV and hepatitis surveillance data to identify new HIV diagnoses during November 2018-October 2021 in a retrospective cohort analysis. We plotted Kaplan-Meier curves and performed Cox regressions to understand effects of HCV coinfection and receipt of Ryan White support services on time to reach HIV viral suppression, adjusting for linkage to HIV care, retention in HIV care, race and ethnicity, gender, age at time of HIV diagnosis, and injection drug use history. Results: Kaplan-Meier plots revealed that median time to HIV viral suppression was shorter among persons with HIV monoinfection, compared with HIV and HCV coinfection (80 days vs 235 days; Conclusions: Addressing social determinants of health through federally sponsored Ryan White services can improve health for persons with HIV monoinfection and HCV coinfection.
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