Evidence map›Paper›PMID 41756196›Full record

ArticleCase reports in medicine2026

Disproportionate Elevated Troponin T Without Clinical Ischemia: A Diagnostic Challenge in the Emergency Department.

Bryan Nicolalde, Ashraf Elamin, Dae Yong-Park, Michael DeCarolis, Samuel Hahn

Abstract read
In one paragraph

Article in Case reports in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bryan NicolaldeDepartment of Medicine, Robert Larner College of Medicine, University of Vermont, Burlington, Vermont, USA, uvm.edu.ORCID https://orcid.org/0000-0002-7043-5515
Ashraf ElaminDepartment of Medicine, Bridgeport Hospital/Yale University Program, Bridgeport, Connecticut, USA.ORCID https://orcid.org/0000-0002-1029-2559
Dae Yong-ParkDepartment of Internal Medicine, Division of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut, USA, yale.edu.
Michael DeCarolisDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA, yale.edu.
Samuel HahnDepartment of Medicine, Bridgeport Hospital/Yale University Program, Bridgeport, Connecticut, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac troponins (cTns) are essential for evaluating chest pain, but elevated levels can arise from noncardiac causes or laboratory artifacts. Confirmatory testing for assay interference is often unavailable for false-positive cases, complicating diagnosis and management. Case Summary: A 62-year-old female presented with chest pain and disproportionally elevated high-sensitivity troponin T (hs-cTnT) levels (8396 ng/L). Clinical evaluation, including EKG, echocardiography, and nuclear myocardial perfusion images showed no evidence of acute ischemia. Noncardiac causes of elevation of troponins, as well laboratory artifacts, were considered as differential diagnostics. A clinically driven approach was adopted to resolve this case. Conclusion: In cases of disproportionally troponin elevation, a clinically driven approach incorporating risk stratification and alternative diagnostic tools, such as nuclear imaging, can effectively guide management and avoid unnecessary interventions.

Identifiers

PMID41756196
PMCPMC12933175

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.