Evidence map›Paper›PMID 41756163›Full record

ArticleFrontiers in cardiovascular medicine2025

Characterisation of interrelations among myocardial work parameters in patients with hypertrophic cardiomyopathy: differences between non-obstructive and obstructive disease.

Viktória Nagy, Gergely Rácz, Krisztina Boda, Hedvig Takács, Bianka Polestyuk, Noémi Schvartz, László Dániel Vidács, Jenő Antal Pintér, Attila Pálinkás, Árpád Kormányos and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Viktória NagyDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Gergely RáczDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Krisztina BodaDepartment of Medical Physics and Informatics, University of Szeged, Szeged, Hungary.
Hedvig TakácsDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Bianka PolestyukDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Noémi SchvartzDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
László Dániel VidácsDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Jenő Antal PintérDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Attila PálinkásDepartment of Medicine, Elisabeth Hospital, Hódmezővásárhely, Hungary.
Árpád KormányosDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Tamás SzűcsborusDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
János BorbásDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Tamás Szili-TörökDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.
Róbert SeppDivision of Non-Invasive Cardiology, Cardiology Centre, Department of Internal Medicine, University of Szeged, Szeged, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/objectives: In recent years, novel echocardiographic parameters, known as myocardial work (MW) parameters, have been introduced into clinical practice for the assessment of contractile function. This study aimed to provide a technical characterization of the interrelations among these MW parameters and evaluate their differences between patients with non-obstructive (nHCM) and obstructive hypertrophic cardiomyopathy (oHCM). Patients and methods: One-hundred-eighteen patients with HCM, including 68 nHCM and 50 oHCM patients were assessed. Global longitudinal strain (GLS) and derived global MW parameters-including global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE)-were determined by 2D-speckle tracking echocardiography. Results: In all HCM cohorts, GLS demonstrated a strong, significant correlation with GWI and GCW ( Conclusions: Given the strong correlation between GLS and GWI/GCW, it is probable that changes in GLS would result in corresponding changes in GWI/GCW, potentially limiting the incremental discriminatory value of these parameters beyond GLS. GWW appears to be the most independent MW parameter from GLS in patients with hypertrophic cardiomyopathy as it weakly correlates with GLS, unlike GWI/GCW.

Indexed as

advanced echocardiographyglobal longitudinal strain (GLS)hypertrophic cardiomyopathyleft ventricular outflow tract obstructionmyocardial work

Identifiers

PMID41756163
PMCPMC12932468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.