ArticleInorganic chemistry frontiers2026
Competitive LC-MS/MS assay to investigate protein metalation dynamics.
Article in Inorganic chemistry frontiers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- All Platinum(II) Ions Are Equal, but Some React Differently: Insights Into the Biomolecular Reactivity of Platinum(II)-Based Anticancer Agents.Bioinorganic chemistry and applications · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Knowledge gaps in the biospeciation of potential metallodrugs may lead to the generalized assumption of their promiscuous reactivity and inherent toxicity, neglecting their pharmaceutical potential. Herein, we developed a rapid and competitive LC-MS/MS assay to determine metalation dynamics of protein mixtures by metallodrugs. Specifically, the time-dependent reactivity of different metallodrugs, based on platinum(ii) (cisplatin, [Pt(ala)(ASA-But)Cl]), ruthenium(ii) ([Ru(HQ)(Cym)Cl], [Ru(NHC)(Cym)Cl
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Registered trials
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