Evidence map›Paper›PMID 41755886›Full record

ReviewPlant-environment interactions (Hoboken, N.J.)2026

CRISPR/Cas Genome Editing and Its Applications in Cereal Crop Improvement.

Sirisha Kaniganti, Himanshu Saini, A K Chaitanya, Niranjan Hegde, Priya Shah, Nakul D Magar, Ramesh Rijal, Jeevan Jyoti Kaushik, Deepak Nanda, Sharad Sachan and 3 more

Abstract readReview
In one paragraph

Review in Plant-environment interactions (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Genome Editing Approaches in Flax (International journal of molecular sciences · 2026
    Review
  4. Review
  5. Genome Editing in Root and Tuber Crop Development in Sub-Saharan Africa.Plant-environment interactions (Hoboken, N.J.) · 2026
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sirisha KanigantiInternational Institute of Tropical Agriculture Nairobi Kenya.
Himanshu SainiSchool of Applied Natural Science Adama Science and Technology University Adama Ethiopia.ORCID https://orcid.org/0009-0000-7852-6262
A K ChaitanyaCentre for Crop Health University of Southern Queensland Toowoomba Queensland Australia.
Niranjan HegdeMcGill University Montreal Quebec Canada.
Priya ShahInternational Crops Research Institute for the Semi-Arid Tropics Patancheru Telangana India.
Nakul D MagarICAR-Indian Institute of Rice Research Hyderabad India.
Ramesh RijalNepal Agricultural Research Council (NARC) Kathmandu Nepal.ORCID https://orcid.org/0009-0004-1410-4377
Jeevan Jyoti KaushikSchool of Basic & Applied Sciences Shri Guru Ram Rai University Dehradun Uttarakhand India.
Deepak NandaTula's Institute of Pharmacy Dehradun Uttarakhand India.
Sharad SachanDepartment of Agricultural Economics and Extension, School of Agriculture Lovely Professional University Punjab India.
Anand KumarFaculty of Agricultural Sciences GLA University Mathura Uttar Pradesh India.
Roopali BhoiteDepartment of Primary Industries and Regional Development South Perth Western Australia Australia.ORCID https://orcid.org/0000-0002-0512-8084
Harsha Rayudu JamedarICAR-Indian Institute of Oilseeds Research Hyderabad India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CRISPR/Cas-based genome editing has emerged as a transformative tool for precise genetic improvement of cereal crops. Recent advances in CRISPR technologies, including Cas9, Cas12, Cas13, base editing, and prime editing, have enabled targeted modification of genes and regulatory elements controlling yield, stress tolerance, and grain nutritional quality in major cereals such as rice, wheat, maize, and barley. This review summarizes current progress in CRISPR-mediated genome editing systems, delivery strategies, and representative applications in cereal crop improvement. Emphasis is placed on how genome editing reprograms enzymatic activities and biological pathways underlying complex agronomic traits rather than acting through single-gene effects. The review also discusses challenges related to trait complexity, regulatory considerations, and prospects for translating genome-edited cereal crops from laboratory research to field-level application. Collectively, this review highlights the potential of CRISPR/Cas genome editing as a powerful approach for developing high-yielding, resilient, and nutritionally improved cereal crops.

Indexed as

cereal cropsCRISPR/Cas genome editinggrain qualitystress toleranceyield improvement

Identifiers

PMID41755886
PMCPMC12932124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.