Evidence map›Paper›PMID 41755865›Full record

ReviewJACS Au2026

Evolution of Methods for the Oxidation of Primary Alcohols to Carboxylic Acids: From Metal Oxides to Biocatalysis.

Jonas Spang, Francesco Mascia, Wolfgang Kroutil

Abstract readReview
In one paragraph

Review in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonas SpangAustrian Centre of Industrial Biotechnology, Institute of Chemistry, University of Graz, Krenngasse 37, 8010 Graz, Austria.ORCID https://orcid.org/0009-0007-9888-077X
Francesco MasciaAustrian Centre of Industrial Biotechnology, Institute of Chemistry, University of Graz, Krenngasse 37, 8010 Graz, Austria.
Wolfgang KroutilAustrian Centre of Industrial Biotechnology, Institute of Chemistry, University of Graz, Krenngasse 37, 8010 Graz, Austria.ORCID https://orcid.org/0000-0002-2151-6394

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carboxylic acids are central building blocks in fine chemical synthesis. Although the direct oxidation of primary alcohols to carboxylic acids appears straightforward from a retrosynthetic perspective, it is often associated with significant challenges. In this Perspective, we discuss concepts of one-pot approaches for the oxidation of primary alcohols to carboxylic acids. These approaches are grouped into chemical and biocatalytic concepts, which are structured according to the stoichiometric oxidant employed. The evolution of these methods is traced from traditional chemical oxidations to modern catalytic and biocatalytic strategies, underscoring the parallel shift in oxidant selection and the resulting improvements in selectivity, practical utility, and sustainability.

Indexed as

BiocatalysisCarboxylic AcidsChemocatalysisMetal OxidesOxidationPrimary Alcohols

Identifiers

PMID41755865
PMCPMC12933326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.