Evidence map›Paper›PMID 41755637›Full record

ArticleNucleic acids research2026

Glycine max Jumonji C domain-containing proteins JMJ19/20 exhibit endopeptidase activity and interact with LUXs to mediate flowering time.

Yapeng Han, Qian Jia, Mengshi Liu, Yuan Fang, Tianqi Shen, Shiru Tan, Qianya Gao, Jing Liu, Chenjiang You, Yingxiang Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yapeng HanGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Qian JiaGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Mengshi LiuGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Yuan FangGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Tianqi ShenGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Shiru TanGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Qianya GaoGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Jing LiuGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Chenjiang YouGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.
Yingxiang WangGuangdong Basic Research Center of Excellence for Precise Breeding of Future Crops, Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory for the Development Biology and Environmental Adaptation of Agricultural Organisms, South China Institute for Soybean Innovation Research, College of Life Sciences, South China Agricultural University, Guangzhou 510642, Guangdong, China.ORCID 0000-0001-6085-5615

Funding

Basic and Applied Basic Research Foundation SL2024A04J02032Guangdong Pearl River Talent Program 2021ZT09N333National Natural Science Foundation of China 32170334National Natural Science Foundation of China 32300290National Science and Technology Major Project 2024ZD040780104South China Agricultural University 2023B10564004
6 · The paper itself

Abstract

Histone demethylases serve essential functions in plant growth and development across various species. However, their roles in Glycine max remain largely unexplored. This study identified GmJMJ19 and GmJMJ20, encoding JmjC domain-containing proteins. They exhibit circadian rhythmic expression patterns and interact with LUX ARRHYTHMO 2 (GmLUX2) both in vitro and in vivo. Although GmJMJ19/20 bind to histones, they lack conventional histone demethylase activity. Rather, GmJMJ19/20 function as endopeptidases that specifically cleave histone H3 peptides at unmethylated lysine 27 residues, in a manner independent of Fe²⁺ and α-ketoglutarate, the cofactors required for typical JmjC enzymes. Structural modeling supports the occlusion of the catalytic pocket that prevents access to methylated substrates. The simultaneous knockout of GmJMJ19/20 significantly delays flowering time. Comparative transcriptomic analyses reveal that the GmJM19/20-GmLUX2 module enhances GmFULc expression via independent of the canonical evening complex. Haplotype analysis suggests that GmJMJ19 underwent selection during domestication, potentially contributing to soybean geographical adaptation.

Indexed as

EndopeptidasesFlowersGlycine maxJumonji Domain-Containing Histone DemethylasesPlant ProteinsCircadian RhythmGene Expression Regulation, PlantHistonesModels, MolecularEndopeptidasesHistonesJumonji Domain-Containing Histone DemethylasesPlant Proteins

Identifiers

PMID41755637
PMCPMC12956348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.