Evidence map›Paper›PMID 41755528›Full record

Trial reportJournal of sleep research2026

Digital Cognitive Behavioural Therapy for Insomnia Compared to Sleep Health Education in Older Adults With Mild Cognitive Impairment and Insomnia: A Feasibility Randomised Controlled Trial.

Camilla M Hoyos, Nicole Espinosa, Nathaniel S Marshall, Haley M LaMonica, Christopher J Gordon, Simon D Kyle, Ronald R Grunstein, Sharon L Naismith

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of sleep research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05568381 (Sleep Disturbance in MCI), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05568381 nacompletednot on this map

Sleep Disturbance in MCI: A Pilot Study of a Cognitive Behavioural Therapy Digital Intervention (SUCCEED)

TypeinterventionalSponsorUniversity of SydneyRan2023 to 2023Enrolled40ConditionsCognitive Dysfunction, Insomnia, Mild Cognitive Impairment, Cognitive DisorderArmsdigital CBT-I, Online Sleep Health Education package
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Camilla M HoyosCentre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Macquarie University, Sydney, New South Wales, Australia.
Nicole EspinosaSchool of Psychology, Faculty of Science, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-8815-3305
Nathaniel S MarshallCentre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Macquarie University, Sydney, New South Wales, Australia.
Haley M LaMonicaCentral Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Christopher J GordonCentre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Macquarie University, Sydney, New South Wales, Australia.
Simon D KyleSir Jules Thorn Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Ronald R GrunsteinCentre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Macquarie University, Sydney, New South Wales, Australia.
Sharon L NaismithSchool of Psychology, Faculty of Science, The University of Sydney, Sydney, New South Wales, Australia.

Funding

BigHealthNational Health and Medical Research Council Centre of Research Excellence-CogSleep APP1152945Wellcome Trust
6 · The paper itself

Abstract

While symptoms of insomnia are common in older adults with mild cognitive impairment (MCI) and predict future cognitive decline, a robust evidence base for treating insomnia in MCI is lacking. This study investigated the feasibility of recruiting and delivering a digital cognitive behavioural therapy for insomnia (dCBT-I) in this group. In a parallel open-label randomised-controlled feasibility trial, participants were recruited and screened via the internet and assessed for MCI using videoconference methods. Eligible participants were randomised to dCBT-I (Sleepio, 6 weekly sessions) or control (3 online modules of sleep health education) over a 12-week period. Inclusion criteria included adults aged ≥ 50 years, Insomnia Severity Index (ISI) > 10, and clinical criteria of MCI on a neuropsychological battery. The primary outcomes were the proportion of participants who met screening and randomisation criteria, and their recruitment pathway (clinic vs. online). A secondary outcome was the effect size of the difference in ISI between groups at week 12. Recruitment occurred March-August 2023 (dCBT-I = 19; control = 21; 30 females; mean [SD] age = 59.7 years [7.3]; ISI = 17.0 [3.7]). 37% of participants issued a pre-screening number (n = 246) were eligible to attend online screening. 47% of those issued a screening number (n = 90) were eligible to be randomised (n = 42), with 2 not proceeding (final n = 40). dCBT-I improved 12 weeks ISI compared to control (Cohen's d [95% CI] -1.6 [-2.4 to -0.8]). 79% of participants completed ≥ 4 sessions. This population can be recruited through online pathways and follow the protocol as well as adhere to the intervention of this remotely conducted trial. Trials Registration: ClinicalTrials.gov Registry: (NCT05568381 registered 03/10/2022).

Indexed as

Cognitive Behavioral TherapyCognitive DysfunctionHealth EducationPatient Education as TopicSleep Initiation and Maintenance DisordersAgedDigital HealthDigital MediaFeasibility StudiesFemaleHumansMaleMiddle AgedTreatment Outcomedementiadigital health technologiesmemorysleep disturbance

Identifiers

PMID41755528
PMCPMC13357848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.