Evidence map›Paper›PMID 41755358›Full record

ArticleEmerging microbes & infections2026

Asymptomatic malaria: a hidden reservoir for the transmission and circulation of artemisinin partial-resistant

Ernest Mazigo, Wang-Jong Lee, Hojong Jun, Fadhila Fitriana, Jadidan Hada Syahada, Johnsy Mary Louis, Fauzi Muh, Feng Lu, Kyu Joon Lee, Joo-Won Nam and 11 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Ernest MazigoDepartment of Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Wang-Jong LeeDepartment of Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Hojong JunDepartment of Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Fadhila FitrianaDepartment of Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Jadidan Hada SyahadaDepartment of Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Johnsy Mary LouisDepartment of Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Fauzi MuhDepartment of Epidemiology and Tropical Medicine, Faculty of Public Health, Universitas Diponegoro, Semarang, Indonesia.
Feng LuDepartment of Pathogen Biology and Immunology, School of Medicine, Yangzhou University, Yangzhou, People's Republic of China.
Kyu Joon LeeDepartment of Tropical Medicine, College of Medicine, Soonchunhyang University, Cheonan, Republic of Korea.
Joo-Won NamCollege of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Joon-Hee HanInstitute of Biological Resources, Chuncheon Bioindustry Foundation, Chuncheon, Republic of Korea.
Tae-Hyung KwonInstitute of Biological Resources, Chuncheon Bioindustry Foundation, Chuncheon, Republic of Korea.
Se Jin LeeDepartment of Obstetrics and Gynecology, Kangwon National University Hospital, Kangon National University School of Medicine, Chuncheon, Republic of Korea.
Sunghun NaDepartment of Obstetrics and Gynecology, Kangwon National University Hospital, Kangon National University School of Medicine, Chuncheon, Republic of Korea.
Wanjoo ChunDepartment of Pharmacology, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.
Won Sun ParkDepartment of Physiology, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Eun-Taek HanDepartment of Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Jim ToddDepartment of Biostatistics, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania.
Alphaxard ManjuranoDepartment of Parasitic Diseases and Vector Control, National Institute for Medical Research (NIMR), Mwanza, Tanzania.
Winifrida KidimaDepartment of Zoology, College of Natural and Applied Sciences, University of Dar es Salaam, Dar es Salaam, Tanzania.
Jin-Hee HanDepartment of Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asymptomatic malaria infections contribute substantially to silent transmission, but the prevalence of artemisinin resistance (ART-R) markers in these carriers remains poorly understood. A community-based cross-sectional study was conducted in Tanzania from December 2022 to July 2023, enrolling 3,489 participants from high-transmission regions of Geita and Kigoma and a low-transmission region of Arusha. Four villages per region were randomly selected, and venous blood samples were tested using rapid diagnostic tests, microscopy, and qPCR, revealing overall positivity rate of 24.4%, 15.8%, and 26.2%, respectively, which indicate a significant proportion of submicroscopic infections. Among the 802 isolates successfully sequenced for

Indexed as

AntimalarialsArtemisininsAsymptomatic InfectionsDrug ResistanceMalaria, FalciparumPlasmodium falciparumAdolescentATP-Binding Cassette, Sub-Family C ProteinsChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleTanzaniaAntimalarialsartemisininArtemisininsATP-Binding Cassette, Sub-Family C ProteinsMdr1 protein, Plasmodium falciparumPlasmodium falciparum: pfk13: pfmdr1: drug resistance markers: asymptomatic malaria: molecular surveillance: antimalarial drug resistance: Tanzania

Identifiers

PMID41755358
PMCPMC12951663

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.