Evidence map›Paper›PMID 41755040›Full record

ArticleSensors (Basel, Switzerland)2026

Biopsy Needle Integrated with Rotational Oblique Spectral Ultrasound (ROSUS) Imaging.

Benjamin C Kreager, Wei-Yi Chang, Jian Tian, Huaiyu Wu, Xiaoning Jiang

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin C KreagerDepartment of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0009-0003-9183-7198
Wei-Yi ChangNordson Acoustic Microscopy Division, Elk Grove Village, IL 60007, USA.
Jian TianCTS Advanced Materials, Lisle, IL 60532, USA.
Huaiyu WuDepartment of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0003-2616-1171
Xiaoning JiangDepartment of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0003-3605-3801

Funding

Integrated Dual-frequency Ultrasound Catheter for Accelerated Sonothrombolysis (iDUCAS)R01HL141967 · NHLBI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Xiaoning Jiang, Zhen Xu · 2018 to 2026
$4.1M
NIH Common Fund R01HL141967
6 · The paper itself

Abstract

Biopsy procedures are essential for definitive cancer diagnosis but remain limited by the risk of accidental blood vessel puncture, which can lead to hemorrhage and procedural failure. Conventional imaging guidance often provides insufficient vascular contrast, making vessel avoidance during needle insertion challenging. A rotational oblique spectral ultrasound (ROSUS) imaging system was developed to improve vessel detection and needle guidance during biopsy procedures. The device integrates a high-frequency PMN-PT 1-3 composite transducer mounted at a 45° angle within the 18-gauge needle tip, enabling simultaneous forward- and side-looking capability. By combining synchronized rotational-axial scanning with multifrequency signal ratio (MFSR) processing, ROSUS achieved volumetric images with blood-tissue contrast ratio improvement over 1.2 dB compared to conventional B-mode signal processing while maintaining high spatial resolution of 85 µm and 424 µm in axial and lateral directions, respectively. These results demonstrate that frequency-domain spectral processing can improve vessel and tissue differentiation, offering an 18-gauge needle-integrated platform for safer and more accurate biopsy needle-based procedures.

Indexed as

Biopsy, NeedleBlood VesselsHumansNeedlesPhantoms, ImagingUltrasonographyblood vessel detectionfine needle aspirationhigh-frequency ultrasoundsingle-element ultrasoundspectral ultrasound imaging

Identifiers

PMID41755040
PMCPMC12943839

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.