Evidence map›Paper›PMID 41754942›Full record

ReviewPharmaceutics2026

Artificial Intelligence in Lung Cancer: A Narrative Review of Recent Advances in Diagnosis, Biomarker Discovery, and Drug Development.

Srikanth Basety, Renuka Gudepu, Aditya Velidandi

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Srikanth BasetyTris Pharma, Monmouth Junction, NJ 08852, USA.ORCID 0009-0007-1491-7687
Renuka GudepuDepartment of Microbiology, Pingle Government College for Women (A), Warangal 506370, India.
Aditya VelidandiDepartment of Biotechnology, Vaagdevi Degree and P.G. College, Warangal 506001, India.ORCID 0000-0002-0969-6142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review highlights the rapidly evolving role of artificial intelligence (AI) in transforming lung cancer care, with a specific focus on its integrated applications across diagnosis, biomarker discovery, and drug development. The novelty of this work lies in its holistic examination of how AI bridges these traditionally separate domains, from radiology and pathology to genomics and clinical trials, to create a more cohesive and personalized oncology pipeline. We detail how AI algorithms significantly enhance early detection by improving the accuracy and efficiency of pulmonary nodule characterization on computed tomography scans and enable precise cancer subtyping via computational pathology. In biomarker discovery, AI-driven analysis of radiomic features and genomic data facilitates the non-invasive prediction of tumor genotype, PD-L1 expression, and immunotherapy response, moving beyond invasive tissue biopsies. Furthermore, AI is accelerating the drug development lifecycle by identifying novel therapeutic targets and optimizing patient selection for clinical trials. The review also explores AI's critical role in personalizing treatment regimens, including predicting outcomes for radiotherapy and immunotherapy, thereby tailoring therapy to individual patient profiles. We critically address the challenges of clinical translation, including model interpretability, data standardization, and ethical considerations, which are pivotal for real-world implementation. Finally, we contend that the future of lung cancer management hinges on robust, multi-institutional validation of AI tools and the development of trustworthy, explainable systems.

Indexed as

artificial intelligencebiomarker discoverydeep learningdrug developmentlung cancer diagnosismachine learningpersonalized medicineradiomics

Identifiers

PMID41754942
PMCPMC12944480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.