Evidence map›Paper›PMID 41754935›Full record

ArticlePharmaceutics2026

The Combination of Immunomodulatory Secretome and Liposome-Bound TRAIL Improves Knee Osteoarthritis Symptoms in an Ovine Model.

Joaquín Marco-Brualla, Felícito García-Álvarez, Sara Fuente, Pablo Fernández, Arantza Vitoria, Francisco José Vázquez, Juan Pedro Lapuente-Fernández, Luis Martínez-Lostao, Antonio Romero, Alberto Anel

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joaquín Marco-BruallaBiochemistry and Molecular and Cell Biology Department, Aragón Health Research Institute (IIS-Aragón), University of Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-1710-4821
Felícito García-ÁlvarezFaculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-2587-7506
Sara FuenteThe Agri-Food Institute of Aragón (IA2), Veterinary Teaching Hospital, University of Zaragoza, 50013 Zaragoza, Spain.ORCID 0000-0002-6409-6000
Pablo FernándezReady for Trading (R4T), Living Cells Molecular and Cell Biology Research Laboratories, Fuenlabrada University Hospital, 28942 Madrid, Spain.
Arantza VitoriaThe Agri-Food Institute of Aragón (IA2), Veterinary Teaching Hospital, University of Zaragoza, 50013 Zaragoza, Spain.ORCID 0000-0003-1286-4968
Francisco José VázquezThe Agri-Food Institute of Aragón (IA2), Veterinary Teaching Hospital, University of Zaragoza, 50013 Zaragoza, Spain.ORCID 0000-0002-8712-2275
Juan Pedro Lapuente-FernándezReady for Trading (R4T), Living Cells Molecular and Cell Biology Research Laboratories, Fuenlabrada University Hospital, 28942 Madrid, Spain.ORCID 0000-0003-3054-4589
Luis Martínez-LostaoFaculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-3043-147X
Antonio RomeroThe Agri-Food Institute of Aragón (IA2), Veterinary Teaching Hospital, University of Zaragoza, 50013 Zaragoza, Spain.ORCID 0000-0001-7188-0461
Alberto AnelBiochemistry and Molecular and Cell Biology Department, Aragón Health Research Institute (IIS-Aragón), University of Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-5175-8394

Funding

Gobierno de Aragón B31_20RGobierno de Aragón B31_23RPeaches Biotech 2022/0396
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LUV-TRAILosteoarthritissecretomesynovial hyperplasiatibial plateau damage

Identifiers

PMID41754935
PMCPMC12944125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.