Evidence map›Paper›PMID 41754926›Full record

ArticlePharmaceutics2026

Nanostructured Lipid Carriers Containing Norfloxacin and 2-Aminothiophene Derivative Reduces Fluoroquinolone Resistance in Multidrug-Resistant

Aléxia Gonçalves Dias, Izabele de Souza Araújo, Rodrigo Santos Aquino de Araújo, Malu Maria Lucas Dos Reis, Cícera Datiane de Morais Oliveira Tintino, Saulo Relison Tintino, Gildênia Alves de Araújo, Priscilla Augusta de Sousa Fernandes, Henrique Douglas Melo Coutinho, Elquio Eleamen Oliveira and 1 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aléxia Gonçalves DiasPostgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.ORCID 0009-0000-8761-3683
Izabele de Souza AraújoPostgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.ORCID 0009-0005-0857-0336
Rodrigo Santos Aquino de AraújoLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Brazil.ORCID 0000-0002-2403-8746
Malu Maria Lucas Dos ReisLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Brazil.ORCID 0000-0003-4480-680X
Cícera Datiane de Morais Oliveira TintinoLaboratory of Microbiology and Molecular Biology, Universidade Regional do Cariri, Crato 63105-000, Brazil.
Saulo Relison TintinoLaboratory of Microbiology and Molecular Biology, Universidade Regional do Cariri, Crato 63105-000, Brazil.ORCID 0000-0002-7733-9331
Gildênia Alves de AraújoLaboratory of Microbiology and Molecular Biology, Universidade Regional do Cariri, Crato 63105-000, Brazil.
Priscilla Augusta de Sousa FernandesPostgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.
Henrique Douglas Melo CoutinhoLaboratory of Microbiology and Molecular Biology, Universidade Regional do Cariri, Crato 63105-000, Brazil.ORCID 0000-0002-6634-4207
Elquio Eleamen OliveiraLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Brazil.ORCID 0000-0002-7214-4455
Francisco Jaime Bezerra Mendonça-JuniorLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Brazil.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Fundação de Apoio à Pesquisa do Estado da Paraíba 001National Council for Scientific and Technological Development 001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

2-amino-thiophene derivativeefflux pump inhibitorsmultidrug resistancenanostructured lipid carriers

Identifiers

PMID41754926
PMCPMC12944099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.