ArticlePharmaceuticals (Basel, Switzerland)2026
Development and Validation of a UPLC-MS/MS Method for the Quantification of Amantadine in Rat Plasma: Application to a Pharmacokinetic Study Under High-Altitude Hypoxia and Mechanistic Insights.
Chang Wang, Wen Yan, Yingfei Zhang, Jinwen Wang, Jingyang Fang, Yuliang Ma, Qian Ji, Yuemei Sun, Wenbin Li, Rong Wang
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Chang WangDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.ORCID 0000-0001-8127-7690 Wen YanDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.
Yingfei ZhangDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.
Jinwen WangDepartment of Pharmacy, The 920th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Kunming 650032, China.ORCID 0009-0004-3051-3437 Jingyang FangDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.ORCID 0009-0006-6024-5968 Yuliang MaDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.
Qian JiDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.
Yuemei SunDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.
Wenbin LiDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.
Rong WangDepartment of Pharmacy, The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.
Funding
the Gansu Provincial Major Project 23ZDFA013-5the National Nature Science Foundation of China 82173738the Natural Science Foundation of Gansu Province 23JRRA545
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
amantadinehigh-altitude hypoxiapharmacokineticsrenal excretionUPLC-MS/MS
Identifiers
PMID41754852
PMCPMC12944594
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