Evidence map›Paper›PMID 41754791›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

An Integrated QSAR-MD-DCCM Pipeline: A Predictive Computational Platform for the Rational Design and Dynamic Functional Validation of Dual-Target Directed Ligands.

Shrikant S Nilewar, Santosh Chobe, Prashik Dudhe, Perli Kranti Kumar, Sandesh Lodha, Akansha D Raut, Dennys Fernández-Conde, Mohd Farhan, Ghazala Muteeb, Tushar Janardan Pawar

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shrikant S NilewarDepartment of Pharmaceutical Chemistry, Maliba Pharmacy College, Uka Tarsadia University, Bardoli 394350, Gujrat, India.ORCID 0000-0002-5794-9191
Santosh ChobeDepartment of Chemistry, M.G.V.'s Loknete Vyankatrao Hiray, Arts, Science and Commerce College, Panchavati, Nashik 422003, Maharashtra, India.
Prashik DudheSchool of Pharmaceutical Science, Sandip University, Nashik 422213, Maharashtra, India.ORCID 0000-0002-6007-5747
Perli Kranti KumarDepartment of Pharmaceutical Analysis, JKKN College of Pharmacy, Komarapalayam 638183, Tamil Nadu, India.ORCID 0009-0004-1202-535X
Sandesh LodhaDepartment of Pharmaceutical Chemistry, Maliba Pharmacy College, Uka Tarsadia University, Bardoli 394350, Gujrat, India.ORCID 0000-0002-7783-6485
Akansha D RautDepartment of Chemistry, School of science, Sandip University, Nashik 422213, Maharashtra, India.
Dennys Fernández-CondeDirección de Mecatrónica, Universidad Politécnica de Querétaro, Carretera Estatal 420 S/N, El Rosario 76240, Querétaro, Mexico.ORCID 0000-0002-8877-7994
Mohd FarhanDepartment of Chemistry, College of Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-1519-9644
Ghazala MuteebDepartment of Nursing, College of Applied Medical Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-3328-3559
Tushar Janardan PawarDirección de Mecatrónica, Universidad Politécnica de Querétaro, Carretera Estatal 420 S/N, El Rosario 76240, Querétaro, Mexico.ORCID 0000-0003-0753-9538

Funding

Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia XXXXX
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acetylcholinesterase (AChE)dynamic cross-correlation map (DCCM)machine learning (ML)molecular dynamics (MD)Multi-target-directed ligand (MTDL)quantitative structure–activity relationship (QSAR)tubulin

Identifiers

PMID41754791
PMCPMC12943165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.