Evidence map›Paper›PMID 41754595›Full record

ArticleViruses2026

Pathogenicity and Genotyping of Fowl Adenovirus-D Serotype 2/11 Circulating in Commercial Broilers in Egypt.

Eman Abd ElMenum Shosha, Ibrahim Eldaghayes, Saleh Esmate Ali Abdel-Rahaman, Amel Hussein, Heba M El Naggar, Mohammed A Gamaleldin, Ahmed Fotouh, Amina A Radwan

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eman Abd ElMenum ShoshaVirology Department, Faculty of Veterinary Medicine, New Valley University, El-Khargia 72511, Egypt.ORCID 0000-0001-5862-3137
Ibrahim EldaghayesDepartment of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli P.O. Box 13662, Libya.ORCID 0000-0002-1750-1448
Saleh Esmate Ali Abdel-RahamanCentral Laboratory for Evaluation of Veterinary Biologics, Veterinary Serum and Vaccines Research Institute, Agriculture Research Center (ARC), Cairo 11381, Egypt.
Amel HusseinCentral Laboratory for Evaluation of Veterinary Biologics, Veterinary Serum and Vaccines Research Institute, Agriculture Research Center (ARC), Cairo 11381, Egypt.
Heba M El NaggarCentral Laboratory for Evaluation of Veterinary Biologics, Veterinary Serum and Vaccines Research Institute, Agriculture Research Center (ARC), Cairo 11381, Egypt.ORCID 0000-0003-4838-9038
Mohammed A GamaleldinDepartment of Poultry Disease, Animal Health Research Institute, Agricultural Research Center, Assiut 71526, Egypt.
Ahmed FotouhPathology and Clinical Pathology Department, Faculty of Veterinary Medicine, New Valley University, El-Khargia 72511, Egypt.ORCID 0000-0002-0697-4303
Amina A RadwanCentral Laboratory for Evaluation of Veterinary Biologics, Veterinary Serum and Vaccines Research Institute, Agriculture Research Center (ARC), Cairo 11381, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fowl adenoviruses are opportunistic emerging viruses that spread widely in fowls, infecting birds of all ages, including young broiler chicks. This study aims to genotype the current adenovirus strains associated with inclusion body hepatitis hydropericardium syndrome (IBH-HPS) among infected broilers in Upper Egypt and to evaluate their pathogenic features. In 2024, 100 tissue samples were collected across Assiut and Sohag governorates in Upper Egypt for genetic characterization and pathogenicity evaluation. FAdVs were detected in 22% (11/50) of flocks. Typical FAdV lesions of dead embryos were observed after seven days post egg inoculation. Regarding the PCR assay of the hexon gene, only 8 of 30 samples were confirmed positive at 897 bp, yielding a 26.6% positivity rate. The remaining samples were considered negative using established RT-qPCR protocols for other viral pathogens. Partial sequencing of the hexon gene revealed that FAdV isolates (

Indexed as

Adenoviridae InfectionsAviadenovirusChickensPoultry DiseasesAnimalsCapsid ProteinsEgyptGenotypePhylogenySerogroupVirulenceCapsid Proteinshexon capsid protein, AdenovirusEgyptfowl adenoviruseshexon geneIBH-HPSpathogenicityphylogenetic analysis

Identifiers

PMID41754595
PMCPMC12944925

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.