Evidence map›Paper›PMID 41754511›Full record

ArticleViruses2026

A Mouse Model for "Definitive" Polyomavirus Nephropathy with End-Organ Injury.

Volker Nickeleit, Dalton Butcher, Bawana Thompson, Vicki G Davis, Piotr Mieczkowski, Harsharan K Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Volker NickeleitDepartment of Pathology and Laboratory Medicine, Division of Nephropathology, The University of North Carolina School of Medicine (UNC-SOM), Brinkhous-Bullitt Building, CB# 7525, Chapel Hill, NC 27599, USA.ORCID 0000-0001-9997-286X
Dalton ButcherDepartment of Pathology and Laboratory Medicine, Division of Nephropathology, The University of North Carolina School of Medicine (UNC-SOM), Brinkhous-Bullitt Building, CB# 7525, Chapel Hill, NC 27599, USA.
Bawana ThompsonDepartment of Pathology and Laboratory Medicine, Division of Nephropathology, The University of North Carolina School of Medicine (UNC-SOM), Brinkhous-Bullitt Building, CB# 7525, Chapel Hill, NC 27599, USA.
Vicki G DavisDepartment of Pathology and Laboratory Medicine, Division of Nephropathology, The University of North Carolina School of Medicine (UNC-SOM), Brinkhous-Bullitt Building, CB# 7525, Chapel Hill, NC 27599, USA.
Piotr MieczkowskiDepartment of Genetics, The University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.ORCID 0000-0003-2418-0096
Harsharan K SinghDepartment of Pathology and Laboratory Medicine, Division of Nephropathology, The University of North Carolina School of Medicine (UNC-SOM), Brinkhous-Bullitt Building, CB# 7525, Chapel Hill, NC 27599, USA.ORCID 0000-0002-3123-5027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mouse models for "definitive" polyomavirus nephropathy with lytic viral replication and end-organ disease (PyVN) do not exist. We aimed at defining a PyVN model in Black-Swiss mice (n = 126) by injecting newborn animals with murine polyomavirus (strain A2; 1 × 10

Indexed as

Disease Models, AnimalKidney DiseasesPolyomavirusPolyomavirus InfectionsAnimalsAntibodies, ViralFemaleKidneyMiceVirus ReplicationAntibodies, ViralBK-Polyomavirushistologylytic viral replicationmouse modelnephropathytubular injuryurinary Haufen

Identifiers

PMID41754511
PMCPMC12945198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.