Evidence map›Paper›PMID 41754441›Full record

ReviewPathogens (Basel, Switzerland)2026

Epidemiological Characteristics of Dengue Disease in Mexico (2014-2025): A Descriptive Analysis of a Hyperendemic Country.

Rosa Cremades, Elena Sandoval-Pinto, Ana Maria Ortega-Prieto, Jose M Jimenez-Guardeño, Héctor Raúl Pérez-Gómez, Juan Carlos Lona Reyes, Erick Sierra-Díaz, Jose Angel Regla-Nava

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rosa CremadesDepartment of Microbiology and Pathology, University Center for Health Science (CUCS), University of Guadalajara, Guadalajara 44340, Mexico.
Elena Sandoval-PintoDepartment of Cellular and Molecular Biology, University of Guadalajara, Guadalajara 45200, Mexico.
Ana Maria Ortega-PrietoInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Málaga, Spain.ORCID 0000-0002-9023-0103
Jose M Jimenez-GuardeñoInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Málaga, Spain.ORCID 0000-0002-1726-8033
Héctor Raúl Pérez-GómezInstitute of Infectious and Experimental Pathology, University Center of Health Sciences, University of Guadalajara, Guadalajara 44280, Mexico.
Juan Carlos Lona ReyesPediatric Infectology Service, Hospital Civil de Guadalajara, Guadalajara 44340, Mexico.
Erick Sierra-DíazEpidemiology División, UMAE HES, Western National Medical Center, Guadalajara 44340, Mexico.
Jose Angel Regla-NavaDepartment of Microbiology and Pathology, University Center for Health Science (CUCS), University of Guadalajara, Guadalajara 44340, Mexico.ORCID 0009-0009-4152-2757

Funding

FORT23/00013 funded by the Programa Fortalece del Ministerio de Ciencia e Innovación and the ISCIII, the grant CNS2023-143738 funded by the MCIN/AEI/10.13039/501100011033 and the European Union NextGenerationEU/PRTR, the grant RYC2021-031227-I funded by t PI-0128-2024Miguel Servet Contract (CP24/00058) and the grant funded by the Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union. PI25/00815This study was supported by funding from the Universidad de Guadalajara (PROSNI Project No. 282716)
6 · The paper itself

Abstract

Dengue is considered the most prevalent mosquito-borne arboviral disease worldwide, representing a public health challenge as its incidence has tripled in the last 30 years. The World Health Organization reports 390 million infections annually in more than 129 countries, with approximately 96 million symptomatic cases and around 40,000 deaths. Mexico is a hyperendemic country, with high prevalence and significant outbreaks. In 2024, a surge was observed, with approximately 125,000 infections and nearly 480 deaths. The states with the most cases and deaths were Colima and Jalisco, respectively, placing significant strain on healthcare services and driving up costs. The disease's epidemiology from 2014 to 2025 is characterized by marked seasonality and periodicity, and by the simultaneous circulation of all four serotypes. In recent years, a notable increase in DENV-3 has been observed. In 2025, there were 21,981 confirmed cases; Sonora recorded the highest incidence, while Jalisco and Sinaloa reported the highest number of deaths. This study provides a unique decadal analysis of the epidemiological characteristics of dengue in Mexico, highlighting potential challenges and emphasizing the importance of epidemiological surveillance and future approaches, such as vaccine provision in the country, to mitigate the high mortality rate and associated costs.

Indexed as

DengueDengue VirusEndemic DiseasesDisease OutbreaksHumansIncidenceMexicoPrevalenceSeasonsSerogrouparbovirusdengue virusDENVepidemiologyMexicooutbreakprevention

Identifiers

PMID41754441
PMCPMC12942781

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.