ArticlePathogens (Basel, Switzerland)2026
HTD1265 Disrupts GimC-Dependent Cellular Processes in
Kaori Itto-Nakama, Naoya Hosoyamada, Shinsuke Ohnuki, Fumiyuki Shirai, Minagi Mukaiyama, Hiroyuki Hirano, Hiroyuki Osada, Charles Boone, Takeo Usui, Yoko Yashiroda and 1 more
Abstract read
In one paragraphArticle in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Kaori Itto-NakamaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwano-ha, Kashiwa 277-8562, Chiba, Japan.
Naoya HosoyamadaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwano-ha, Kashiwa 277-8562, Chiba, Japan.
Shinsuke OhnukiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwano-ha, Kashiwa 277-8562, Chiba, Japan.ORCID 0000-0001-6254-081X Fumiyuki ShiraiRIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako 351-0198, Saitama, Japan.ORCID 0000-0003-0593-2467 Minagi MukaiyamaInstitute of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8572, Ibaraki, Japan.
Hiroyuki HiranoRIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako 351-0198, Saitama, Japan.
Hiroyuki OsadaInstitute of Microbial Chemistry (BIKAKEN), 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021, Japan.ORCID 0000-0002-3606-4925 Charles BooneRIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako 351-0198, Saitama, Japan.
Takeo UsuiInstitute of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8572, Ibaraki, Japan.
Yoko YashirodaRIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako 351-0198, Saitama, Japan.
Yoshikazu OhyaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwano-ha, Kashiwa 277-8562, Chiba, Japan.ORCID 0000-0003-0837-1239 Funding
JSPS KAKENHI 22K06522JSPS KAKENHI 23H04882JSPS KAKENHI 23K23483JSPS KAKENHI 25K01916JSPS Program for Forming Japan's Peak Research Universities (J-PEAKS) JPJS00420240017
6 · The paper itselfAbstract
HTD1265 is a newly identified antifungal compound that displays potent activity against
Indexed as
Antifungal AgentsCandidaSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTubulinAntifungal AgentsSaccharomyces cerevisiae ProteinsTubulinantifungal agentsCandida kruseiGimC (prefoldin)Saccharomyces cerevisiae
Identifiers
PMID41754437
PMCPMC12942709
What OpenQuestion holds
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LicenceCC BY
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