Evidence map›Paper›PMID 41754426›Full record

Trial reportPathogens (Basel, Switzerland)2026

High-Dose Rifampicin Plus Albendazole Rapidly Clears Lymphatic Filariasis Circulating Filarial Antigen in a Randomised Clinical Trial: A Promising Step Toward Short-Course Macrofilaricidal Therapy.

Emmanuel Donawobuge Kutu, Derrick Adu Mensah, Vera Serwaa Opoku, John Boateng, John Opoku, Jubin Osei-Mensah, Charles Gyasi, Prince Obeng, Abu Abudu Rahamani, Monica Ahiadorme and 8 more

Abstract readRandomized Controlled TrialClinical Trial, Phase II
In one paragraph

Trial report in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Emmanuel Donawobuge KutuDepartment of Clinical Microbiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0003-4510-8616
Derrick Adu MensahKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0002-8972-1757
Vera Serwaa OpokuKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0001-7950-6650
John BoatengDepartment of Clinical Microbiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0003-1309-2840
John OpokuKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0002-6341-3131
Jubin Osei-MensahKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0003-3470-2994
Charles GyasiKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0002-7549-7117
Prince ObengKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.
Abu Abudu RahamaniDepartment of Clinical Microbiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0002-4560-3118
Monica AhiadormeKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.
Prince Dennis AtisuDepartment of Clinical Microbiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0009-0000-8726-1585
Michael Agyemang ObengKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0002-0265-1822
Eunice Kyaakyile KuutieroKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0009-0001-3872-5571
Nana Kwame Ayisi-BoatengDepartment of Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0000-0002-0961-4434
Derrick Boateng KontohDepartment of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.ORCID 0009-0001-4884-3774
Sampson Twumasi-AnkrahDepartment of Statistics and Actuarial Science, Faculty of Physical and Computational Sciences, College of Science, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.
Linda Batsa DebrahDepartment of Clinical Microbiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.
Alexander Yaw DebrahKumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Private Mail Bag, University Post Office, Kumasi 00233, Ghana.

Funding

European and Developing Countries Clinical Trials Partnership 2 (EDCTP2) TMA2018SF-2451-ASTAWOL
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AlbendazoleAntigens, HelminthElephantiasis, FilarialFilaricidesRifampinAdolescentAdultAnimalsDrug Therapy, CombinationFemaleGhanaHumansMaleMiddle AgedPilot ProjectsTreatment OutcomeAlbendazoleAntigens, HelminthFilaricidesRifampinalbendazolecirculating filarial antigenhigh doselymphatic filariasismacrofilaricidalrifampicin

Identifiers

PMID41754426
PMCPMC12943464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.