Evidence map›Paper›PMID 41754397›Full record

ArticlePathogens (Basel, Switzerland)2026

Detection of HIV-1 Resistance Mutations to Antiretroviral Therapy and Cell Tropism in Russian Patients Using Next-Generation Sequencing.

Artem Fadeev, Veronika Eder, Maria Pisareva, Valery Tsvetkov, Alexey Masharskiy, Kseniya Komissarova, Anna Ivanova, Nikita Yolshin, Andrey Komissarov, Alexey Mazus and 1 more

Abstract read
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In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Artem FadeevSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0003-3558-3261
Veronika EderSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0002-9970-3325
Maria PisarevaSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.
Valery TsvetkovSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0001-5195-9316
Alexey MasharskiySmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0003-1837-3895
Kseniya KomissarovaSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0002-1465-5548
Anna IvanovaSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.
Nikita YolshinSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0002-1050-5817
Andrey KomissarovSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0003-1733-1255
Alexey MazusMoscow City Center for AIDS Prevention and Control, 8th Sokolina Gora Str., 15, 105275 Moscow, Russia.
Dmitry LioznovSmorodintsev Research Institute of Influenza, Prof. Popova Str., 15/17, 197376 Saint Petersburg, Russia.ORCID 0000-0003-3643-7354

Funding

Ministry of Health of the Russian Federation TVKQ-2024-0009
6 · The paper itself

Abstract

The use of antiretroviral therapy (ART) as the only effective way to control human immunodeficiency virus (HIV) infection results in HIV drug resistance. Next-generation sequencing (NGS) has become a common method for identifying drug-resistant variants and reducing analysis costs. The aim of this study was to develop an NGS-based protocol for identifying resistance mutations and cell tropism of HIV-1 in adult patients with and without treatment experience in Russia in 2024-2025. Plasma samples from adult HIV-infected patients from Russia were analyzed. Consensus nucleotide sequences of

Indexed as

Anti-HIV AgentsDrug Resistance, ViralHigh-Throughput Nucleotide SequencingHIV-1HIV InfectionsMutationViral TropismAdultFemaleHumansMaleRussiaAnti-HIV Agentsantiretroviral therapydrug resistance mutationshuman immunodeficiency virusnext generation sequencing

Identifiers

PMID41754397
PMCPMC12943137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.