Evidence map›Paper›PMID 41754322›Full record

ReviewPlants (Basel, Switzerland)2026

Beyond HY5: COP1 Posttranslational Control of Anthocyanin Biosynthesis Proteins in Horticultural Crops.

Gabriel Lasmar Dos Reis, Agustín Zsögön, Antonio Chalfun-Junior, Lázaro Eustáquio Pereira Peres, Vagner Augusto Benedito

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriel Lasmar Dos ReisDepartment of Biology, Universidade Federal de Lavras (UFLA), Lavras 37200-900, MG, Brazil.
Agustín ZsögönNational Institute of Science and Technology on Plant Physiology Under Stress Conditions, Department of Plant Biology, Universidade Federal de Viçosa, Viçosa 36570-900, MG, Brazil.ORCID 0000-0001-7828-7425
Antonio Chalfun-JuniorDepartment of Biology, Universidade Federal de Lavras (UFLA), Lavras 37200-900, MG, Brazil.ORCID 0000-0002-1794-9429
Lázaro Eustáquio Pereira PeresLaboratory of Hormonal Control of Plant Development, Luiz de Queiroz College of Agriculture, Department of Biological Sciences, University of São Paulo, Piracicaba 13418-900, SP, Brazil.ORCID 0000-0002-8761-5934
Vagner Augusto BeneditoDepartment of Biology, Universidade Federal de Lavras (UFLA), Lavras 37200-900, MG, Brazil.ORCID 0000-0002-2131-7651

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 308701/2022-4Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 309005/2022-1Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 445056/2024-0Coordination for the Improvement of Higher Education Personnel (CAPES) 88887.642843/2021-00USDA National Institute of Food and Agriculture Hatch project 11400036 (WVA00754)
6 · The paper itself

Abstract

Anthocyanins are widespread specialized metabolites that provide pigmentation and antioxidant capacity, contributing to pollinator and seed-disperser attraction and to plant resistance to diverse environmental stresses. In human diets, anthocyanins are valued for their antioxidant and health-promoting properties. The biosynthetic pathway of anthocyanins is relatively conserved across plant species and is controlled by structural genes that encode the enzymes of the pathway along with regulatory genes, particularly transcription factors. This network integrates developmental and environmental signals, with light serving as a dominant cue: anthocyanins typically accumulate in light-exposed tissues and are repressed in darkness. A key node in this light-dependent switch is CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1), an E3 ubiquitin ligase that, in the dark, promotes polyubiquitination and proteasome-mediated turnover of positive regulators of anthocyanin production. Although ELONGATED HYPOCOTYL 5 (HY5) is a canonical COP1 target and major activator of anthocyanin biosynthesis, COP1 control of this pathway extends well beyond HY5. Evidence from

Indexed as

bioactive compoundlightpost-translational regulationubiquitination

Identifiers

PMID41754322
PMCPMC12944699

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.