Evidence map›Paper›PMID 41754061›Full record

ArticleHealthcare (Basel, Switzerland)2026

Predictability of Deep Bite Correction and Curve of Spee Flattening in Clear Aligner Therapy: An Open-Label and One Arm Retrospective Study.

Alessandro Nota, Floriana Bosco, Laura Pittari, Chiara Clerici, Miryam Romito, Francesco Manfredi Monticciolo, Giorgio Gastaldi, Simona Tecco

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alessandro NotaDental School, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, 20132 Milan, Italy.ORCID 0000-0003-3651-1251
Floriana BoscoDental School, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, 20132 Milan, Italy.ORCID 0000-0003-4497-9970
Laura PittariDental School, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, 20132 Milan, Italy.ORCID 0000-0003-1992-9146
Chiara ClericiDental School, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, 20132 Milan, Italy.
Miryam RomitoDental School, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, 20132 Milan, Italy.
Francesco Manfredi MonticcioloDental School, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, 20132 Milan, Italy.ORCID 0009-0009-3901-9503
Giorgio GastaldiDental School, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, 20132 Milan, Italy.ORCID 0000-0002-6285-1404
Simona TeccoDental School, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, 20132 Milan, Italy.ORCID 0000-0003-2986-1114

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to evaluate the predictability of Clear Aligner Therapy (CAT) in deep bite correction and Spee Curve flattening by comparing final intraoral scans with planned outcomes in ClinCheck.

methodsSTL files from pre-treatment, post-treatment (first aligner cycle), and planned final positions of 18 patients (12 females; 6 males; mean age 30.9 ± 12.3 years) were analyzed. The software Medit Link (version 3.4.4) was used to measure overbite as the vertical distance between the incisal edges of the maxillary and mandibular central incisors and the Curve of Spee in both arches by drawing a reference line between the most distal molar and the central incisor on each side, recording the perpendicular distance from the distal cusp. Measurements were repeated on post-treatment and ClinCheck STL files. Data analysis was performed using a Student's

resultsA significant discrepancy was observed in overbite correction (55% achieved), with a significant difference between expected and actual outcomes (

conclusionsClinCheck overestimates deep bite correction. Upper Curve of Spee flattening is highly predictable, while the lower curve flattening has lower predictability.

Indexed as

clear alignersdeep bitedigital dentistrypredictabilitySpee curvetreatment planning

Identifiers

PMID41754061
PMCPMC12941074

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.