Evidence map›Paper›PMID 41753956›Full record

ReviewHealthcare (Basel, Switzerland)2026

Evidence on Measures for the Prevention of Pressure Injuries in Mechanically Ventilated Patients in Prone Positioning: A Systematic Review.

Simone Amato, Daniele Napolitano, Alessio Lo Cascio, Elena Conoscenti, Angela Lappa, Emilio D'avino, Mirko Masciullo, Antonello Pucci, Valentina De Bartolo, Claudia Torretta and 3 more

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Simone AmatoCardiac Intensive Care Unit, Heart Transplant Centre and ECMO Service, San Camillo Forlanini Hospital, 00152 Rome, Italy.ORCID 0009-0003-8296-710X
Daniele NapolitanoCentre for Digestive Diseases (CEMAD), Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0003-2481-5354
Alessio Lo CascioDirection of Health Professions, La Maddalena Cancer Center, 90146 Palermo, Italy.ORCID 0000-0001-5581-4114
Elena ConoscentiDepartment of Internal Medicine and Pediatrics, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-4745-9308
Angela LappaDepartment of Heart and Vessels, Cardiovascular Intensive Care Unit, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Emilio D'avinoDepartment of Heart and Vessels, Cardiovascular Intensive Care Unit, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Mirko MasciulloCardiac Intensive Care Unit, Heart Transplant Centre and ECMO Service, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Antonello PucciShock and Trauma Unit, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Valentina De BartoloMultispecialty Surgery Unit, European Hospital, 00149 Rome, Italy.
Claudia TorrettaDepartment of Health Professions, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Lucia MitelloDepartment of Health Professions, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Anna Rita MarucciDepartment of Health Professions, San Camillo Forlanini Hospital, 00152 Rome, Italy.ORCID 0000-0001-9311-3909
Francesco GravanteIntensive Care Unit, Department of Critical Care, Local Health Authority of Caserta, 81100 Caserta, Italy.ORCID 0000-0002-3548-6018

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTherapeutic prone positioning is widely used to improve oxygenation in patients with acute respiratory distress syndrome but is associated with an increased risk of pressure injuries, particularly affecting facial and anterior body regions.

methodsThis systematic review was conducted according to PRISMA 2020 and Joanna Briggs Institute guidelines and was prospectively registered in PROSPERO (CRD42023442604). PubMed, CINAHL, Web of Science, Scopus, and the Cochrane Library were searched from inception to June 2025, including grey literature. Primary studies involving adult, mechanically ventilated patients undergoing therapeutic prone positioning and evaluating pressure injury prevention strategies were included. Methodological quality was assessed using JBI critical appraisal tools. Owing to clinical and methodological heterogeneity, findings were synthesized using a Synthesis Without Meta-analysis (SWiM) approach.

resultsEight studies with heterogeneous designs were included. Preventive interventions mainly comprised prophylactic dressings, repositioning and support devices, and comprehensive care bundles. Most strategies were associated with a reduction in pressure injury incidence, particularly in facial and anterior anatomical areas. Greater effectiveness was observed when interventions were implemented within structured protocols supported by staff training and multidisciplinary coordination.

conclusionsPreventive strategies appear effective in reducing pressure injuries associated with prone positioning in critically ill patients. The implementation of standardized, bundled prevention protocols may improve patient safety in intensive care settings.

Indexed as

care bundlescritical careintensive care nursingpressure injuriesprevention strategiesprone positioningprophylactic dressingsskin integrity

Identifiers

PMID41753956
PMCPMC12941124

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.