Evidence map›Paper›PMID 41753770›Full record

ArticleMicroorganisms2026

Multi-Kingdom Fecal Microbiota Alterations in Horses with Severe Equine Asthma.

Rafaela Santos, Laszlo Hunyadi, Emily Sundman, Luis Morales Luna, Sarah Cate Hyde, Makala Cain, Kagan Migl, Jacob Ancira, Craig Tipton, Fernanda Rosa

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rafaela SantosSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.ORCID 0009-0000-8267-7004
Laszlo HunyadiSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.ORCID 0000-0002-2572-5628
Emily SundmanSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.ORCID 0000-0001-7949-4266
Luis Morales LunaSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.
Sarah Cate HydeSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.
Makala CainSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.
Kagan MiglSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.
Jacob AnciraDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
Craig TiptonRTL Genomics, MicroGenDX, Lubbock, TX 79413, USA.
Fernanda RosaSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.ORCID 0000-0002-8906-4056

Funding

American Quarter Horse Association 2024-0000000551
6 · The paper itself

Abstract

Severe equine asthma (SEA) is a chronic inflammation of airways affecting ~14-20% of adult horses in the Northern Hemisphere. SEA is characterized by a mixed phenotype of T helper cell responses with marked neutrophilia in the bronchoalveolar lavage fluid (BALF) of affected horses. Human studies have demonstrated the impact of gut microbiota in many diseases, including asthma susceptibility and severity. However, the potential role of the gut-lung axis in the development and persistence of SEA remains to be determined. This study aimed to identify key bacterial, archaeal, and fungal microbiota alterations in the feces of horses with severe neutrophilic asthma (n = 4) compared to healthy horses (n = 8). Archaea alpha diversity was lower in the feces of SEA-affected horses, but with high abundance of archaea genus

Indexed as

allergiesasthmaequinefecal microbiotainflammation

Identifiers

PMID41753770
PMCPMC12943238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.