ArticleMicroorganisms2026
Feeding Type Shapes Infant Gut Microbiota and Metabolite Profiles in a Simulated Colonic Model.
Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
The establishment of the infant gut microbiota is strongly influenced by feeding type, with human milk (HM) and infant formula (IF) driving distinct microbial profiles. This study compared the effects of donated raw human milk (HM) and Holder-pasteurised HM (Past-HM) on microbial composition using a 4-stage in vitro gut model inoculated with pooled faecal samples from five healthy 3-6-month-old infants. Colonic digesta were sampled over a 48-h period following introduction of raw HM, Past-HM and IFs for microbial diversity by quantitative polymerase chain reaction (qPCR) and 16S rRNA gene sequencing, and short-chain fatty acid (SCFA) analysis by gas chromatography. Microbial profiling revealed 2026 operational taxonomic units (OTUs) across eight phyla and 165 genera. Past-HM and goat milk-based IF (GIF) promoted
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