Evidence map›Paper›PMID 41753572›Full record

ArticleMicroorganisms2026

Hospital Wing Opening Sparks Antimicrobial Resistance in Wastewater Microbial Community Within the First Twelve Months.

Laura Lohbrunner, Claudia Baessler, Elena Becker, Christina Döhla, Nina Droll, Ralf M Hagen, Niklas Klein, Nico T Mutters, Alexander Reyhe, Ruth Weppler and 1 more

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laura LohbrunnerInstitute for Hygiene and Public Health, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
Claudia BaesslerDepartment of Hospital Pharmacy, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.
Elena BeckerDepartment of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.
Christina DöhlaDepartment of Hospital Pharmacy, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.
Nina DrollHospital Management, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.
Ralf M HagenDepartment of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.ORCID 0000-0003-4875-1519
Niklas KleinDepartment of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.
Nico T MuttersInstitute for Hygiene and Public Health, Medical Faculty, University of Bonn, 53127 Bonn, Germany.ORCID 0000-0002-0156-9595
Alexander ReyheDepartment of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.
Ruth WepplerDepartment of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.
Manuel DöhlaInstitute for Hygiene and Public Health, Medical Faculty, University of Bonn, 53127 Bonn, Germany.ORCID 0000-0001-8029-5264

Funding

University of Bonn Open Access Publication Fund
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) in hospital wastewater is a recognized public health concern, yet the dynamics of its emergence remain poorly understood. This study aimed to characterize the quantitative and qualitative changes in the microbial community of a newly built internal medicine intensive care hospital wing following the start of patient treatment. Wastewater samples were collected regularly from eight relevant sites, including seven patient-associated locations within the intensive care ward and the central sanitary sewer where all effluent converged. Culture-based analyses targeted the "ESCAPE-SO" bacterial and fungal groups ("Enterococci", "Staphylococci", "Candida", "Acinetobacter", "Pseudomonas", "Enterobacteriaceae", "Stenotrophomonas", "Others"). Comparisons were made between a 12-month pre-operation period (only flushing every 72 h to prevent contamination of the drinking water system) and the first 12 months of patient treatment. The results showed a significant increase in mean bacterial concentrations from 53 [0-349] CFU/mL before patient treatment to 8423 [3054-79,490] CFU/mL during patient treatment (

Indexed as

antibiotic resistance emergenceantimicrobial resistanceclinical antibiotic useenvironmental resistomeESKAPE pathogenshospital wastewaterintensive care unitPseudomonas spp.wastewater microbiomewastewater surveillance

Identifiers

PMID41753572
PMCPMC12943030

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.